KIR2DL1/KIR2DS5 Antibody (124) [DyLight 650] Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
This antibody was obtained from a rabbit immunized with purified, recombinant Human KIR2DL1/KIR2DS5 (Accession#: NP_055033.2; Met1-His245). |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
KIR2DL1 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A purified |
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for KIR2DL1/KIR2DS5 Antibody (124) [DyLight 650]
Background
The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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