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JNK1 Antibody

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Western Blot: JNK1 Antibody [NB100-1925] - Detection of JNK-1 using NB100-1925.

Product Details

Summary
Reactivity Ce, Hu(-), Ma(-), Mu(-), Rt(-)Species Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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JNK1 Antibody Summary

Immunogen
A recombinant protein made to the C-terminus (residues 228-451) of the C. elegans JNK1 alpha protein.
Localization
Neuronal
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MAPK8
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:200-1:500
  • Immunohistochemistry-Paraffin 1:200-1:500
  • Western Blot 1:2000
Application Notes
This JNK1 antibody is useful for ELISA, Immunohistochemistry-Paraffin and Western blot where a band can be seen at ~53kDa (alpha form) and at ~42kDa (beta form).
Publications
Read Publications using
NB100-1925 in the following applications:

  • WB
    1 publication

Reactivity Notes

This antibody does not appear to detect mammalian JNK protein.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for JNK1 Antibody

  • c-Jun N-terminal kinase 1
  • EC 2.7.11
  • EC 2.7.11.24
  • JNK1 alpha protein kinase
  • JNK1 beta protein kinase
  • JNK1
  • JNK1JNK1A2
  • JNK-46
  • JUN N-terminal kinase
  • MAP kinase 8
  • MAPK 8
  • MAPK8
  • mitogen-activated protein kinase 8 isoform JNK1 alpha1
  • mitogen-activated protein kinase 8 isoform JNK1 beta2
  • mitogen-activated protein kinase 8
  • PRKM8
  • PRKM8JNK
  • protein kinase JNK1
  • SAPK1
  • SAPK1JNK21B1/2
  • Stress-activated protein kinase 1
  • Stress-activated protein kinase JNK1

Background

The insulin signaling pathway plays a pivotal role in lifespan regulation and stress resistance in many diverse organisms. Components of the JNK (c-Jun N-terminal kinase) signaling pathway have been shown to interact with the insulin signaling pathway. The JNK family is a subgroup of the mitogen-activated protein kinase superfamily and is part of a signal transduction cascade that is activated by cytokines and by exposure to environmental stresses. Thus, JNK1 plays a role in regulating both life span and stress resistance.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for JNK1 Antibody (NB100-1925)(2)

We have publications tested in 1 confirmed species: C. elegans.

We have publications tested in 1 application: WB.


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WB
(1)
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Filter By Species
C. elegans
(1)
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for JNK1 Antibody (NB100-1925)

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Blogs on JNK1.

MAPK8/JNK1 - A multifunctional kinase and drug target for cancer therapeutics
The c-Jun N-terminal kinase (JNK) family is a group of regulatory kinases with important functions in cell morphogenesis, inflammation, differentiation, and cell death (1). Aberrant activation of JNK family proteins in cancers has led to interest i...  Read full blog post.

Use Of c-Myc Antibodies In Non-Invasive Cancer Studies
Novus Biologicals specializes in offering top quality antibody reagents to many of the transcription factor proteins that are widely expressed in cancer cells.C-Myc is one of several transcription factor proteins covered by our antibody catalog. Enc...  Read full blog post.

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Bioinformatics

Gene Symbol MAPK8
Entrez