JNK1 Antibody (1E5) - BSA Free

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ICC/IF.

Showing Publications 1 - 2 of 2.

Publications using NBP2-22209	Applications	Species
SOZEN E, DEMIREL-YALCINER T, DAMLA DEMIR D Et al. SREBP1c silencing reduces endoplasmic reticulum stress and related apoptosis in oleic acid induced lipid accumulation Marmara Medical Journal 2021-10-31 (ICC/IF, Mouse)	ICC/IF	Mouse
Sozen E, Demirel-Yalciner T, Sari D, Ozer NK Cholesterol accumulation in hepatocytes mediates IRE1/p38 branch of endoplasmic reticulum stress to promote nonalcoholic steatohepatitis Free radical biology & medicine 2022-08-19 [PMID: 35995397] (ICC/IF, Mouse) Details: AML12 cells (mouse hepatocytes)	ICC/IF	Mouse

Array NBP2-22209

• JNK1 Antibodies
• JNK1 Lysates
• JNK1 Protein
• JNK1 Proteins and Enzyme