Insulin Receptor beta Antibody [Janelia Fluor® 549] Summary
Immunogen |
The immunogen this antibody was made to, maps to a region between residue 1332 and 1382 of human Insulin Receptor, beta Subunit using the numbering given in entry NP_000199.2 (GeneID 3643). |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
INSR |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin
- Immunoprecipitation
|
Reactivity Notes
Mouse reactivity reported from a verified customer review.
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for Insulin Receptor beta Antibody [Janelia Fluor® 549]
Background
The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for Insulin Receptor beta Antibody (NBP2-12793JF549) (0)
Secondary Antibodies
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