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Insulin Receptor beta Antibody [Janelia Fluor® 549]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 549
Concentration
1.0 mg/ml

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Insulin Receptor beta Antibody [Janelia Fluor® 549] Summary

Immunogen
The immunogen this antibody was made to, maps to a region between residue 1332 and 1382 of human Insulin Receptor, beta Subunit using the numbering given in entry NP_000199.2 (GeneID 3643).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
INSR
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation

Reactivity Notes

Mouse reactivity reported from a verified customer review.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Insulin Receptor beta Antibody [Janelia Fluor® 549]

  • CD220 antigen
  • CD220
  • EC 2.7.10
  • EC 2.7.10.1
  • HHF5
  • insulin receptor
  • IR

Background

The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Insulin Receptor beta Antibody (NBP2-12793JF549) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol INSR