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IL-4R alpha Antibody (25463) [Phycoerythrin]

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Daudi human Burkitt's lymphoma cell line was stained with Mouse Anti-Human IL-4 Ra PE-conjugated Monoclonal Antibody (Catalog # FAB230P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Daudi human Burkitt's lymphoma cell line was stained with Mouse Anti-Human IL-4 Ra PE-conjugated Monoclonal Antibody (Catalog # FAB230P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
25463
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB230U-100UG
Alexa Fluor 405
FAB230V-100UG
Alexa Fluor 488
FAB230G-100UG
Alexa Fluor 532
FAB230X
Alexa Fluor 594
FAB230T-100UG
Alexa Fluor 647
FAB230R-100UG
Alexa Fluor 700
FAB230N-025
Alexa Fluor 700
FAB230N-100
Alexa Fluor 750
FAB230S-100UG
Allophycocyanin
FAB230A-100
Allophycocyanin
FAB230A-025
Allophycocyanin/Cy7
FAB230APCCY7
Biotin
FAB230B
CoraFluor 1
FAB230CL1
DyLight 350
FAB230D
DyLight 405
FAB230E
DyLight 488
FAB230K
DyLight 550
FAB230L
DyLight 594
FAB230M
DyLight 650
FAB230W
DyLight 680
FAB230Y
DyLight 755
FAB230Z
HRP
FAB230H
Janelia Fluor 525
FAB230JF525
Janelia Fluor 549
FAB230I
Janelia Fluor 646
FAB230J
Janelia Fluor 669
FAB230JF669
PE/Atto594
FAB230PEATT594
PE/Cy5.5
FAB230PECY55
PE/Cy7
FAB230PECY7
Phycoerythrin
FAB230P-025
Unconjugated
MAB230-100
mFluor Violet 450 SE
FAB230MFV450
mFluor Violet 500 SE
FAB230MFV500
mFluor Violet 610 SE
FAB230MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB230-100
Carrier Free
FAB230A-100
Carrier Free
FAB230N-100
Carrier Free
FAB230N-025
Carrier Free
FAB230P-025
Carrier Free
FAB230A-025
Carrier Free
MAB230-SP
Carrier Free
MAB230-100
Carrier Free
MAB230-500
Carrier Free
FAB230V-100UG
Carrier Free
FAB230U-100UG
Carrier Free
FAB230T-100UG
Carrier Free
FAB230S-100UG
Carrier Free
FAB230R-100UG
Carrier Free
FAB230G-100UG
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IL-4R alpha Antibody (25463) [Phycoerythrin] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL‑4 R
Gly24-His232
Accession # P24394
Specificity
Detects human IL‑4 R alpha in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-9 R, recombinant mouse IL-4 R, rhIL-5 R alpha , rhIL-5 R beta , rhIL-13 R alpha 1, or rhIL-13 R alpha 2 is observed.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
IL4R
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Publications
Read Publications using
FAB230P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-4R alpha Antibody (25463) [Phycoerythrin]

  • CD124 antigen
  • CD124
  • IL-4 R alpha
  • IL-4 receptor subunit alpha
  • IL4R alpha
  • IL-4R alpha
  • IL-4R subunit alpha
  • IL4R
  • IL-4Ra
  • IL4RACD124
  • IL-4R-alpha
  • interleukin 4 receptor
  • interleukin-4 receptor alpha chain
  • interleukin-4 receptor subunit alpha

Background

Interleukin 4 receptor (IL-4 R) is the transmembrane ligand binding subunit of the heterodimeric IL-4 receptor complex. In the type I receptor complex, IL-4 R associates with the common gamma chain, whereas in the type II receptor complex, it associates with IL-13 R alpha 1. IL-4 R is expressed by B cells, T cells, monocytes and macrophages.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
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Protein Array HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
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Western Blot HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
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IL-13R alpha 1
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Publications for IL-4R alpha Antibody (FAB230P)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(5)
All Applications
Filter By Species
Human
(4)
Mouse
(1)
All Species
Showing Publications 1 - 5 of 5.
Publications using FAB230P Applications Species
S Magri, B Musca, C Bonaudo, A Tushe, MG Russo, E Masetto, V Zagonel, G Lombardi, A Della Pupp, S Mandruzzat Sustained Accumulation of Blood-Derived Macrophages in the Immune Microenvironment of Patients with Recurrent Glioblastoma after Therapy Cancers, 2021-12-07;13(24):. 2021-12-07 [PMID: 34944798] (Flow Cytometry, Human) Flow Cytometry Human
AB Guimarães-, NC Rochael, F Oliveira, J Echevarria, EM Saraiva Neutrophil Extracellular Traps Reprogram IL-4/GM-CSF-Induced Monocyte Differentiation to Anti-inflammatory Macrophages Front Immunol, 2017-05-17;8(0):523. 2017-05-17 [PMID: 28567039] (Flow Cytometry, Human) Flow Cytometry Human
Occhipinti S, Sponton L, Rolla S, Caorsi C, Novarino A, Donadio M, Bustreo S, Satolli M, Pecchioni C, Marchini C, Amici A, Cavallo F, Cappello P, Pierobon D, Novelli F, Giovarelli M Chimeric rat/human HER2 efficiently circumvents HER2 tolerance in cancer patients. Clin Cancer Res, 2014-03-25;20(11):2910-21. 2014-03-25 [PMID: 24668647] (Flow Cytometry, Human) Flow Cytometry Human
Mandruzzato S, Solito S, Falisi E, Francescato S, Chiarion-Sileni V, Mocellin S, Zanon A, Rossi CR, Nitti D, Bronte V, Zanovello P IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. J. Immunol., 2009-05-15;182(10):6562-8. 2009-05-15 [PMID: 19414811] (Flow Cytometry, Human) Flow Cytometry Human
Maki K, Ikuta K MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling. J. Immunol., 2008-07-01;181(1):494-502. 2008-07-01 [PMID: 18566415] (Flow Cytometry, Mouse) Flow Cytometry Mouse

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Bioinformatics

Gene Symbol IL4R
Uniprot