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IA-2/PTPRN Antibody (8E3)

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Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07] - Analysis of PTPRN expression in transfected 293T cell line by PTPRN monoclonal antibody (M07), clone 8E3. Lane 1: PTPRN transfected lysate (Predicted MW: 65.01 KDa). Lane 2: Non-transfected lysate.
Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07] - Analysis of PTPRN expression in transfected 293T cell line by PTPRN monoclonal antibody (M07), clone 8E3. Lane 1: PTPRN transfected lysate (Predicted MW: 65.01 ...read more
Western Blot: IA-2/PTPRN Antibody (8E3) [H00005798-M07] - Western Blot detection against PTPRN (37.4 KDa) .
ELISA: IA-2/PTPRN Antibody (8E3) [H00005798-M07] - Detection limit for recombinant GST tagged PTPRN is 0.03 ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
8E3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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IA-2/PTPRN Antibody (8E3) Summary

Description
Quality control test: Antibody Reactive Against Recombinant Protein.
Immunogen
PTPRN (NP_002837, 205 a.a. ~ 311 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LLQPYLFHQFGSRDGSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPEG
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PTPRN
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
It has been used for ELISA and WB.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IA-2/PTPRN Antibody (8E3)

  • CA 512
  • EC 3.1.3.48
  • FLJ16131
  • IA2
  • IA-2
  • IA-2/PTP
  • ICA 512
  • ICA3
  • ICA512
  • islet cell antigen 2
  • Islet cell antigen 512
  • Islet cell autoantigen 3
  • protein tyrosine phosphatase, receptor type, N
  • protein tyrosine phosphatase-like N
  • PTP IA-2
  • PTPRN
  • receptor-type tyrosine-protein phosphatase-like N
  • R-PTP-N

Background

PTPRN is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PTPRN
Uniprot