Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human Total MMP-7 DuoSet ELISA, 15 Plate
EC 3.4.24
EC 3.4.24.23
Matrilysin
matrin
matrix metallopeptidase 7 (matrilysin, uterine)
matrix metalloproteinase 7 (matrilysin, uterine)
Matrix metalloproteinase-7
MMP7
MMP-7
MPSL1
Pump-1 protease
PUMP1
PUMP-1
uterine matrilysin
Uterine metalloproteinase
Background
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
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