Human PD-1 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

PD-1 (Programmed Death-1 receptor) is a key regulator of the threshold of immune response and peripheral immune tolerance. It is expressed on activated T cells, B cells, monocytes, and dendritic cells and binds to PD-L1 or PD-L2. PD-1 ligation induces co-inhibitory signals in T cells promoting their apoptosis, anergy, and functional exhaustion. Blockade of the PD-1: PD-L1 interaction using anti-PD-1 antibodies enhances understanding of anti-tumor immunity and advances the potential for cancer immunotherapy.

We have publications tested in 2 confirmed species: Human, Mouse.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using DY1086	Applications	Species
K Krueger, Z Mayer, M Kottmaier, M Gerckens, S Boeck, P Luppa, S Holdenried Robust Preanalytical Performance of Soluble PD-1, PD-L1 and PD-L2 Assessed by Sensitive ELISAs in Blood Biomedicines, 2022-10-11;10(10):. 2022-10-11 [PMID: 36289796] (Human)		Human
K Krueger, Z Mayer, M Gerckens, S Boeck, P Luppa, S Holdenried High Quality Performance of Novel Immunoassays for the Sensitive Quantification of Soluble PD-1, PD-L1 and PD-L2 in Blood Biomedicines, 2022-09-26;10(10):. 2022-09-26 [PMID: 36289665] (Human)		Human
R Ohkuma, K Ieguchi, M Watanabe, D Takayanagi, T Goshima, R Onoue, K Hamada, Y Kubota, A Horiike, T Ishiguro, Y Hirasawa, H Ariizumi, J Tsurutani, K Yoshimura, M Tsuji, Y Kiuchi, S Kobayashi, T Tsunoda, S Wada Increased Plasma Soluble PD-1 Concentration Correlates with Disease Progression in Patients with Cancer Treated with Anti-PD-1 Antibodies Biomedicines, 2021-12-16;9(12):. 2021-12-16 [PMID: 34944745] (Human)		Human
N Tan, H Luo, Q Kang, J Pan, R Cheng, H Xi, H Chen, Y Han, Y Yang, X Xu High Levels of Soluble Programmed Death-1 Are Associated with Virological Response in Chronic Hepatitis B patients after Antiviral Treatment Virus research, 2021-12-18;0(0):198660. 2021-12-18 [PMID: 34929214] (Human)		Human
G Larrinaga, JD Solano-Itu, P Errarte, M Unda, A Loizaga-Ir, A Pérez-Fern, E Echevarría, A Asumendi, C Manini, JC Angulo, JI López Soluble PD-L1 Is an Independent Prognostic Factor in Clear Cell Renal Cell Carcinoma Cancers, 2021-02-07;13(4):. 2021-02-07 [PMID: 33562338] (Human)		Human
H Vajavaara, JB Mortensen, SK Leivonen, IM Hansen, M Ludvigsen, H Holte, J Jørgensen, M Bjerre, F d'Amore, S Leppä Soluble PD-1 but Not PD-L1 Levels Predict Poor Outcome in Patients with High-Risk Diffuse Large B-Cell Lymphoma Cancers, 2021-01-22;13(3):. 2021-01-22 [PMID: 33499013] (Human)		Human
ALD Pace, N Tumino, F Besi, C Alicata, LA Conti, E Munari, E Maggi, P Vacca, L Moretta Characterization of Human NK Cell-Derived Exosomes: Role of DNAM1 Receptor In Exosome-Mediated Cytotoxicity Against Tumor Cancers (Basel), 2020-03-12;12(3):. 2020-03-12 [PMID: 32178479] (Human)		Human
Y Guo, AM Walsh, M Canavan, MD Wechalekar, S Cole, X Yin, B Scott, M Loza, C Orr, T McGarry, M Bombardier, F Humby, SM Proudman, C Pitzalis, MD Smith, JR Friedman, I Anderson, L Madakamuti, DJ Veale, U Fearon, S Nagpal Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression PLoS ONE, 2018-02-28;13(2):e0192704. 2018-02-28 [PMID: 29489833] (Human)		Human
S Kruger, ML Legenstein, V Rösgen, M Haas, DP Modest, CB Westphalen, S Ormanns, T Kirchner, V Heinemann, S Holdenried, S Boeck Serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death ligand 1 (sPD-L1) in advanced pancreatic cancer Oncoimmunology, 2017-03-31;6(5):e1310358. 2017-03-31 [PMID: 28638732] (Human)		Human
MY Bartee, KM Dunlap, E Bartee Tumor localized secretion of soluble PD1 enhances oncolytic virotherapy Cancer Res, 2017-03-17;0(0):. 2017-03-17 [PMID: 28314785] (Mouse)		Mouse
Cheng H, Kang P, Chuang Y, Wang Y, Jan M, Wu C, Lin C, Liu C, Liaw Y, Lin S, Chen P, Lee S, Yu M Circulating programmed death-1 as a marker for sustained high hepatitis B viral load and risk of hepatocellular carcinoma. PLoS ONE, 2014-11-26;9(11):e95870. 2014-11-26 [PMID: 25427199] (Human)		Human
Show All 11 Publications. Collapse Publications.

Array DY1086

• PD-1 Antibodies
• PD-1 Antibody Pair
• PD-1 Lysate
• PD-1 Proteins
• PD-1 Proteins and Enzymes
• PD-1 ELISAs