Human IL-23 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 15. Show All 15 Publications. Collapse Publications.

Publications using DY1290	Applications	Species
Joci?, J;Lu?i?, AT;Jovanovi?, I;Juriševi?, M;Stanisavljevi?, I;Stamenkovi?, B;Pavlovi?, S; Interleukin 41 As A Potential Predictor of Bio-Therapy Efficacy In Patients With Rheumatoid Arthritis: A Prospective Observational Study International journal of medical sciences 2024-09-30 [PMID: 39439456] (Human)		Human
Fiorillo, A;Gallego, JJ;Casanova-Ferrer, F;Giménez-Garzó, C;Urios, A;Ballester, MP;Durbán, L;Rios, MP;Megías, J;San Miguel, T;Kosenko, E;Escudero-García, D;Benlloch, S;Felipo, V;Montoliu, C; Mild Cognitive Impairment Is Associated with Enhanced Activation of Th17 Lymphocytes in Non-Alcoholic Fatty Liver Disease International journal of molecular sciences 2023-06-20 [PMID: 37373554] (Human)		Human
M Holopainen, U Impola, P Lehenkari, S Laitinen, E Kerkelä Human Mesenchymal Stromal Cell Secretome Promotes the Immunoregulatory Phenotype and Phagocytosis Activity in Human Macrophages Cells, 2020-09-22;9(9):. 2020-09-22 [PMID: 32972000] (Human)		Human
F Erra Díaz, V Ochoa, A Merlotti, E Dantas, I Mazzitelli, V Gonzalez P, J Sabatté, S Amigorena, E Segura, J Geffner Extracellular Acidosis and mTOR Inhibition Drive the Differentiation of Human Monocyte-Derived Dendritic Cells Cell Rep, 2020-05-05;31(5):107613. 2020-05-05 [PMID: 32375041] (Human)		Human
M De Angelis, I Ferrocino, FM Calabrese, F De Filippi, N Cavallo, S Siragusa, S Rampelli, R Di Cagno, K Rantsiou, L Vannini, N Pellegrini, C Lazzi, S Turroni, N Lorusso, M Ventura, M Chieppa, E Neviani, P Brigidi, PW O'Toole, D Ercolini, M Gobbetti, L Cocolin Diet influences the functions of the human intestinal microbiome Sci Rep, 2020-03-06;10(1):4247. 2020-03-06 [PMID: 32144387] (Human)		Human
G Müller, C Lübow, G Weindl Lysosomotropic beta blockers induce oxidative stress and IL23A production in Langerhans cells Autophagy, 2019-11-07;0(0):1-16. 2019-11-07 [PMID: 31668121] (Human)		Human
B Walch-Rück, R Ströder, L Theobald, J Pahne-Zepp, S Hegde, YJ Kim, RM Bohle, I Juhasz-Bös, EF Solomayer, S Smola Cervical cancer-instructed stromal fibroblasts enhance IL-23 expression in dendritic cells to support expansion of Th17 cells Cancer Res., 2019-01-29;0(0):. 2019-01-29 [PMID: 30696656] (Human)		Human
SY Nuñez, A Ziblat, F Secchiari, NI Torres, JM Sierra, XL Raffo Irao, RE Araya, CI Domaica, MB Fuertes, NW Zwirner Human M2 Macrophages Limit NK Cell Effector Functions through Secretion of TGF-? and Engagement of CD85j J. Immunol., 2017-12-27;0(0):. 2017-12-27 [PMID: 29282306] (Human)		Human
T Nakajima, H Yoshifuji, M Shimizu, K Kitagori, K Murakami, R Nakashima, Y Imura, M Tanaka, K Ohmura, F Matsuda, C Terao, T Mimori A novel susceptibility locus in the IL12B region is associated with the pathophysiology of Takayasu arteritis through IL-12p40 and IL-12p70 production Arthritis Res. Ther., 2017-09-06;19(1):197. 2017-09-06 [PMID: 28874185] (Human)		Human
Philipp Kotthoff, Annkristin Heine, Stefanie Andrea Erika Held, Peter Brossart Dexamethasone induced inhibition of Dectin-1 activation of antigen presenting cells is mediated via STAT-3 and NF-?B signaling pathways. Scientific Reports, 2017-07-03;0(0):2045-2322. 2017-07-03 [PMID: 28674449] (Human)		Human
V Oke, S Brauner, A Larsson, J Gustafsson, A Zickert, I Gunnarsson, E Svenungsso IFN-?1 with Th17 axis cytokines and IFN-? define different subsets in systemic lupus erythematosus (SLE) Arthritis Res. Ther., 2017-06-15;19(1):139. 2017-06-15 [PMID: 28619037] (Human)		Human
Zickert A, Amoudruz P, Sundstrom Y, Ronnelid J, Malmstrom V, Gunnarsson I IL-17 and IL-23 in lupus nephritis - association to histopathology and response to treatment. BMC Immunol, 2015-02-12;16(0):7. 2015-02-12 [PMID: 25887118] (Human)		Human
Jaguin M, Fardel O, Lecureur V Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2. PLoS ONE, 2015-02-24;10(2):e0116560. 2015-02-24 [PMID: 25710172] (Human)		Human
Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells. Br J Haematol, 2014-01-15;165(1):134-44. 2014-01-15 [PMID: 24428589] (Human)		Human
Jiang S, Liu X, Luo L, Qu B, Huang X, Lin Y, Ye S, Liu Y Serum levels of Th17-related cytokines in Behcet disease patients after cataract surgery. Mol. Vis., 2011-05-31;17(0):1425-30. 2011-05-31 [PMID: 21655356] (Human)		Human
Show All 15 Publications. Collapse Publications.

Array DY1290

• IL-23A/IL-23 P19 Antibodies
• IL-23A/IL-23 P19 Lysate
• IL-23A/IL-23 P19 Proteins
• IL-23A/IL-23 P19 ELISAs
• IL-23A/IL-23 P19 Proteins and Enzymes