Human IGFBP-rp1/IGFBP-7 DuoSet ELISA, 5 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. ALS (Acid Labile Subunit) is a liver-derived protein that exists in a ternary complex with Insulin-like Growth Factor (IGF)-binding Protein-3 (IGFBP-3) or IGFBP-5, and either IGF-I or IGF-II. ALS increases the half-life of IGF/IGFBP complexes in circulation.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: ICC.

Showing Publications 1 - 6 of 6.

Publications using DY1334-05	Applications	Species
Hong, Z;Xie, W;Zhuo, H;Wei, X;Wang, K;Cheng, J;Lin, L;Hou, J;Chen, X;Cai, J; Crosstalk between Cancer Cells and Cancer-Associated Fibroblasts Mediated by TGF-?1-IGFBP7 Signaling Promotes the Progression of Infiltrative Gastric Cancer Cancers 2023-08-04 [PMID: 37568781] (ICC, Mouse)	ICC	Mouse
J Rossaint, M Meersch, K Thomas, S Mersmann, M Lehmann, J Skupski, T Tekath, P Rosenberge, JA Kellum, H Pavenstädt, A Zarbock Remote ischemic preconditioning causes transient cell-cycle arrest and renal protection by a NF-kB-dependent Sema5B pathway JCI Insight, 2022-07-22;0(0):. 2022-07-22 [PMID: 35727636] (Mouse)		Mouse
H Huang, Q Lin, X Dai, J Chen, Z Bai, X Li, F Fang, Y Li Derivation and validation of urinary TIMP-1 for the prediction of acute kidney injury and mortality in critically ill children Journal of Translational Medicine, 2022-02-23;20(1):102. 2022-02-23 [PMID: 35197070] (Human)		Human
X Tao, C Chen, W Luo, J Zhou, J Tian, X Yang, FF Hou Combining renal cell arrest and damage biomarkers to predict progressive AKI in patient with sepsis Bmc Nephrology, 2021-12-15;22(1):415. 2021-12-15 [PMID: 34906098] (Human)		Human
J Rumpel, BJ Spray, VY Chock, MJ Kirkley, CL Slagle, A Frymoyer, SH Cho, KM Gist, R Blaszak, B Poindexter, SE Courtney Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia The Journal of pediatrics, 2021-09-20;0(0):. 2021-09-20 [PMID: 34547334] (Human)		Human
Z Bai, F Fang, Z Xu, C Lu, X Wang, J Chen, J Pan, J Wang, Y Li Serum and urine FGF23 and IGFBP-7 for the prediction of acute kidney injury in critically ill children BMC Pediatr, 2018-06-15;18(1):192. 2018-06-15 [PMID: 29907141] (Human)		Human

Array DY1334-05

• IGFBP-rp1/IGFBP-7 Antibodies
• IGFBP-rp1/IGFBP-7 Antibody Pair
• IGFBP-rp1/IGFBP-7 ELISA Kits
• IGFBP-rp1/IGFBP-7 Lysate
• IGFBP-rp1/IGFBP-7 Proteins
• IGFBP-rp1/IGFBP-7 Proteins and Enzymes
• IGFBP-rp1/IGFBP-7 ELISA