Human Haptoglobin DuoSet ELISA, 5 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Haptoglobin is an acute phase glycoprotein that is an inactive member of the peptidase S1 family of serine proteases. It is secreted by multiple cell types and binds with high affinity to circulating Hemoglobin. Association of Haptoglobin with free Hemoglobin protects tissues from Hemoglobin-mediated oxidative damage and facilitates Hemoglobin clearance. In addition, Haptoglobin has anti-inflammatory properties that are independent of Hemoglobin binding. It inhibits prostaglandin synthesis, scavenges nitric oxide, dampens the inflammatory response to endotoxins, and inhibits T cell proliferation and neutrophil respiratory bursts. Deletion of Haptoglobin in mice facilitates the development of autoimmune inflammation.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 3 of 3.

Publications using DY8465-05	Applications	Species
Custers, E;van der Burgh, YGR;Vreeken, D;Schuren, F;van den Broek, TJ;Verschuren, L;de Blaauw, I;Bouwens, M;Kleemann, R;Kiliaan, AJ;Hazebroek, EJ; Gastrointestinal complaints after Roux-en-Y gastric bypass surgery. Impact of microbiota and its metabolites Heliyon 2024-11-15 [PMID: 39559236] (Human)		Human
KN Lee, KH Park, YM Kim, I Cho, TE Kim Prediction of emergency cerclage outcomes in women with cervical insufficiency: The role of inflammatory, angiogenic, and extracellular matrix-related proteins in amniotic fluid PLoS ONE, 2022-05-10;17(5):e0268291. 2022-05-10 [PMID: 35536791] (Human)		Human
JH Back, SY Kim, MB Gu, HJ Kim, KN Lee, JE Lee Proteomic analysis of plasma to identify novel biomarkers for intra-amniotic infection and/or inflammation in preterm premature rupture of membranes Research square, 2023-01-01;0(0):. 2023-01-01 [PMID: 30335284] (Human)		Human

Array DY8465-05

• Haptoglobin Antibodies
• Haptoglobin ELISA Kits
• Haptoglobin Lysate
• Haptoglobin Proteins
• Haptoglobin ELISAs