Human FGF-19 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

FGF-19 (Fibroblast Growth Factor-19) is a secreted heparin-binding protein in the endocrine subfamily of FGFs that also includes FGF-21 and FGF-23. It is produced by epithelial cells of the ileal intestine in response to bile acids and signals through a receptor complex of FGF R4 and Klotho-beta in the liver. FGF-19 suppresses bile acid synthesis and enhances hepatic protein and glycogen synthesis. Dysregulalted FGF-19 activity is associated with the development of hypercholesterolemia, gall stones, bile acid induced diarrhoea (BAD), hepatocellular cancer, colon cancer, and metabolic syndrome.

We have publications tested in 1 confirmed species: Human.

Showing Publication 1 - 1 of 1.

Publication using DY969	Applications	Species
CM Fallon, JS Smyth, A Quach, N Lajczak-Mc, A O'Toole, KE Barrett, H Sheridan, SJ Keely Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: implications for colonic secretory function The Journal of Biological Chemistry, 2022-10-06;0(0):102569. 2022-10-06 [PMID: 36209824] (Human)		Human

Array DY969

• FGF-19 Antibodies
• FGF-19 ELISA Kits
• FGF-19 Lysate
• FGF-19 Proteins
• FGF-19 ELISAs
• FGF-19 Proteins and Enzymes