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Human CA125/MUC16 Quantikine ELISA Kit

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Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

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Human CA125/MUC16 Quantikine ELISA Kit Summary

Background
The Quantikine Human CA125/MUC16 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human CA125 in cell culture supernates, serum, plasma, saliva, urine, and human milk. It contains CHO cell-expressed recombinant human CA125 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human CA125 showed linear curves that were parallel to th...e standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human CA125.
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Specificity
Natural and recombinant human CA125
Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
MUC16

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DCA125 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CA125/MUC16 Quantikine ELISA Kit

  • CA125 ovarian cancer antigen
  • CA125
  • CA-125
  • CA125MUC-16
  • FLJ14303
  • MUC16
  • mucin 16, cell surface associated
  • mucin-16
  • Ovarian cancer-related tumor marker CA125
  • Ovarian carcinoma antigen CA125

Background

The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CA125/MUC16 (DCA125)(8)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.


Filter By Application
Western Blot
(1)
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Human
(8)
All Species
Showing Publications 1 - 8 of 8.
Publications using DCA125 Applications Species
Hiniduma, K;Bhalerao, KS;De Silva, PIT;Chen, T;Rusling, JF; Design and Fabrication of a 3D-Printed Microfluidic Immunoarray for Ultrasensitive Multiplexed Protein Detection Micromachines 2023-11-30 [PMID: 38138356] (Human) Human
L Ning, J Lang, B Long, L Wu Diagnostic value of circN4BP2L2 in type I and type II epithelial ovarian cancer BMC Cancer, 2022-11-24;22(1):1210. 2022-11-24 [PMID: 36434559] (Human) Human
AW Gahlawat, T Witte, L Haarhuis, S Schott A novel circulating miRNA panel for non-invasive ovarian cancer diagnosis and prognosis British Journal of Cancer, 2022-08-05;0(0):. 2022-08-05 [PMID: 35931806] (Human) Human
L Ning, J Lang, L Wu Plasma circN4BP2L2 is a promising novel diagnostic biomarker for epithelial ovarian cancer BMC Cancer, 2022-01-03;22(1):6. 2022-01-03 [PMID: 34980005] (Human) Human
AL D'Souza, JR Chevillet, P Ghanouni, X Yan, M Tewari, SS Gambhir Tumor characterization by ultrasound-release of multiple protein and microRNA biomarkers, preclinical and clinical evidence PLoS ONE, 2018-03-16;13(3):e0194268. 2018-03-16 [PMID: 29547636] (Human) Human
Arslan S, Yu Y, Burdette J, Pavone M, Hope T, Woodruff T, Kim J Novel three dimensional human endocervix cultures respond to 28-day hormone treatment. Endocrinology, 2015-01-30;156(4):1602-9. 2015-01-30 [PMID: 25635622] (Human) Human
Tamir , Ayala, Jag , Ushma, Sarojini , Sreeja, Schindewolf , Craig, Tanaka , Takemi, Gharbaran , Rajendra, Patel , Hiren, Sood , Anil, Hu , Wei, Patwa , Ruzeen, Blake , Patrick, Chirina , Polina, Oh Jeong , Jin, Lim , Heejin, Goy , Andre, Pecora , Andrew, Suh , K Stephe Kallikrein family proteases KLK6 and KLK7 are potential early detection and diagnostic biomarkers for serous and papillary serous ovarian cancer subtypes. J Ovarian Res, 2014-12-05;7(1):109. 2014-12-05 [PMID: 25477184] (Human) Human
Prassas , Ioannis, Brinc , Davor, Farkona , Sofia, Leung , Felix, Dimitromanolakis , Apostolo, Chrystoja , Caitlin, Brand , Randall, Kulasingam , Vathany, Blasutig , Ivan M, Diamandis , Elefther False biomarker discovery due to reactivity of a commercial ELISA for CUZD1 with cancer antigen CA125. Clin Chem, 2013-10-04;60(2):381-8. 2013-10-04 [PMID: 24097894] (Western Blot, Human) Western Blot Human

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Bioinformatics

Gene Symbol MUC16