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Histone H2AE [p Ser1] Antibody (RM216) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity Hu, VbSpecies Glossary
Applications WB, ELISA, ICC/IF, Func
Clone
RM216
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 750

Order Details

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Histone H2AE [p Ser1] Antibody (RM216) [Alexa Fluor® 750] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
An unmodified peptide corresponding to the N-terminus of Histone H2AE
Modification
p Ser1
Specificity
This antibody reacts to Histone H4 or Histone H2AE phosphorylated at Serine 1. No cross reactivity with other phosphorylated Histones.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HIST1H2AE
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Multiplex Immunoassay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Histone H2AE [p Ser1] Antibody (RM216) [Alexa Fluor® 750]

  • H2A histone family, member M
  • H2A/m
  • H2AFA
  • H2AFMHistone H2A/m
  • HIST1H2AE
  • histone 1, H2ab
  • histone cluster 1, H2ab
  • histone H2A type 1-B/E
  • Histone H2A.2
  • Histone H2A/a

Background

Histone H2AE is 124 amino acids long, weighing approximately 13 kDa, and is part of a group of basic nuclear proteins called histones, which are responsible for nucleosome structure of the chromosomal fiber in eukaryotes and is a core component of the nucleosome. Current studies are being done on several diseases and disorders including riddle syndrome, systemic lupus erythematosus, lupus srythematosus, and immunodeficiency. This protein has also been shown to have interactions with HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, and HIST1H4E in pathways such as the proteasome degradation, nucleosome assembly, cell cycle, and systemic lupus erythematosus pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional Histone H2AE Products

Array NBP3-26017AF750

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Bioinformatics

Gene Symbol HIST1H2AE