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HERV Antibody [Alexa Fluor® 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Func, IHC, B/N
Clonality
Polyclonal
Host
Rabbit
Conjugate
Alexa Fluor 594

Order Details

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HERV Antibody [Alexa Fluor® 594] Summary

Immunogen
Synthetic peptide corresponding to residues 42-50 [QRPGNIDAPC] of the HERV protein.
Specificity
Human Endogenous Retroviruses (HERVs), a class of multiple-sclerosis-associated retroviruses
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERVW-1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • In vitro assay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HERV Antibody [Alexa Fluor® 594]

  • endogenous retroviral family W, env(C7), member 1
  • ENV
  • envelope glycoprotein
  • Envelope polyprotein gPr73
  • enverin
  • ENVW
  • Env-W
  • HERV-7q Envelope protein
  • HERV7Q
  • HERV-7q
  • HERV-tryptophan envelope protein
  • HERV-W Env glycoprotein
  • HERV-W envelope protein
  • HERV-W
  • HERV-W_7q21.2 provirus ancestral Env polyprotein
  • HERV-W{7q21.1} provirus ancestral Env polyprotein
  • HERVWENV
  • HERV-W-ENV
  • HERVWenvelope protein
  • human endogenous retrovirus W envC7-1 envelope protein
  • syncytin A
  • Syncytin
  • syncytin-1

Background

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional HERV Products

Array NB100-93579AF594

Research Areas for HERV Antibody (NB100-93579AF594)

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Blogs on HERV

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Bioinformatics

Gene Symbol ERVW-1