HERV Products

Description

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Bioinformatics

Entrez	30816 Human
Uniprot	NP_055405 Human Q9UQF0 Human
Product By Gene ID	30816
Alternate Names	endogenous retroviral family W, env(C7), member 1 ENV envelope glycoprotein Envelope polyprotein gPr73 enverin Enverin ENVW Env-W env-W HERV-7q Envelope protein HERV7Q HERV-7q HERV-tryptophan envelope protein HERV-W Env glycoprotein HERV-W envelope protein HERV-W HERV-W_7q21.2 provirus ancestral Env polyprotein HERV-W{7q21.1} provirus ancestral Env polyprotein HERVWENV HERV-W-ENV HERVWenvelope protein human endogenous retrovirus W envC7-1 envelope protein syncytin A Syncytin syncytin-1 Syncytin-1