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GRB10 Antibody

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Immunocytochemistry/ Immunofluorescence: GRB10 Antibody [NBP2-55491] - Staining of human cell line A549 shows localization to nuclear membrane & vesicles.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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GRB10 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: LHHPYYQDKVEQTPRSQQDPAGPGLPAQSDRLANHQEDDVDLEALVNDMNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRB10
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
GRB10 Recombinant Protein Antigen (NBP2-55491PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for GRB10 Antibody

  • GRB10 adapter protein
  • GRB10 adaptor protein
  • Grb-10
  • GRBIR
  • GRB-IR
  • growth factor receptor-bound protein 10
  • Insulin receptor-binding protein Grb-IR
  • IRBP
  • KIAA0207
  • maternally expressed gene 1
  • MEG1
  • RSS

Background

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for GRB10 Antibody (NBP2-55491) (0)

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for GRB10 Antibody (NBP2-55491) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for GRB10 Antibody (NBP2-55491)

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Blogs on GRB10

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Bioinformatics

Gene Symbol GRB10