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Recombinant Human GNB3 His Protein

Name: Recombinant Human GNB3 His Protein
Brand: Novus Biologicals
SKU: NBP2-23096
Price: 409 USD

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SDS-Page: GNB3 Protein [NBP2-23096]

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	PAGE
Concentration	0.5 mg/ml

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Recombinant Human GNB3 His Protein Summary

Description	A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-340 of Human GNB3 Source: E.coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGEMEQL RQEAEQLKKQ IADARKACAD VTLAELVSGL EVVGRVQMRT RRTLRGHLAK IYAMHWATDS KLLVSASQDG KLIVWDSYTT NKVHAIPLRS SWVMTCAYAP SGNFVACGGL DNMCSIYNLK SREGNVKVSR ELSAHTGYLS CCRFLDDNNI VTSSGDTTCA LWDIETGQQK TVFVGHTGDC MSLAVSPDFN LFISGACDAS AKLWDVREGT CRQTFTGHES DINAICFFPN GEAICTGSDD ASCRLFDLRA DQELICFSHE SIICGITSVA FSLSGRLLFA GYDDFNCNVW DSMKSERVGI LSGHDNRVSC LGVTADGMAV ATGSWDSFLK IWN
Source	E. coli
Protein/Peptide Type	Recombinant Protein
Gene	GNB3
Purity	>80%, by SDS-PAGE

Applications/Dilutions

Dilutions	SDS-Page
Application Notes	Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
Theoretical MW	39.6 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer	20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.4M UREA
Preservative	No Preservative
Concentration	0.5 mg/ml
Purity	>80%, by SDS-PAGE

Alternate Names for Recombinant Human GNB3 His Protein

G protein, beta-3 subunit
GTP-binding regulatory protein beta-3 chain
guanine nucleotide binding protein (G protein), beta polypeptide 3
guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
hypertension associated protein
Transducin beta chain 3

Background

GNB3 is important regulator of alpha subunit, as well as of certain signal transduction receptor and effector. A single-nucleotide polymorphism (C825T) in this protein is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene, but they have not been fully described. Recombinant human GNB3 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol

GNB3

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Recombinant Human GNB3 His Protein

Species Glossary

Images

Product Details

Order Details

Recombinant Human GNB3 His Protein Summary

Applications/Dilutions

Packaging, Storage & Formulations

Alternate Names for Recombinant Human GNB3 His Protein

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for GNB3 Protein (NBP2-23096) (0)

Reviews for GNB3 Protein (NBP2-23096) (0)

FAQs for GNB3 Protein (NBP2-23096) (0)

Additional GNB3 Products

Research Areas for GNB3 Protein (NBP2-23096)

Blogs on GNB3

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Contact Information

Product PDFs

Calculators

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Bioinformatics