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GLP1 Antibody (4) [CoraFluor™ 1]

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Product Details

Summary
Reactivity Hu, Mu, MaSpecies Glossary
Applications ELISA, IHC
Clone
4
Clonality
Monoclonal
Host
Mouse
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-23558AF350
Alexa Fluor 405
NBP2-23558AF405
Alexa Fluor 488
NBP2-23558AF488
Alexa Fluor 532
NBP2-23558AF532
Alexa Fluor 594
NBP2-23558AF594
Alexa Fluor 647
NBP2-23558AF647
Alexa Fluor 700
NBP2-23558AF700
Alexa Fluor 750
NBP2-23558AF750
Biotin
NBP2-23558B
DyLight 350
NBP2-23558UV
DyLight 405
NBP2-23558V
DyLight 488
NBP2-23558G
DyLight 550
NBP2-23558R
DyLight 594
NBP2-23558DL594
DyLight 650
NBP2-23558C
DyLight 680
NBP2-23558FR
DyLight 755
NBP2-23558IR
FITC
NBP2-23558F
HRP
NBP2-23558H
Janelia Fluor 525
NBP2-23558JF525
Janelia Fluor 549
NBP2-23558JF549
Janelia Fluor 585
NBP2-23558JF585
Janelia Fluor 635
NBP2-23558JF635
Janelia Fluor 646
NBP2-23558JF646
Janelia Fluor 669
NBP2-23558JF669
PerCP
NBP2-23558PCP
Unconjugated
NBP2-23558-0.1ml
mFluor Violet 450 SE
NBP2-23558MFV450
mFluor Violet 500 SE
NBP2-23558MFV500
mFluor Violet 610 SE
NBP2-23558MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-23558-0.1ml
BSA Free
NBP2-23558-0.1ml
BSA Free
NBP2-23558-0.025ml
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GLP1 Antibody (4) [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Synthetic GLP-1(7-17)
Epitope
Free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide.
Specificity
This antibody binds the free N-terminus of GLP-1(7-37) and GLP-1(7-36)amide and shows <0.2% cross-reactivity with GLP-1(1-37), GLP-1(9-36)amide, human GIP and exendin-4. Cross-reacts approximately 1% with human GLP-2.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
GCG
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for GLP1 Antibody (4) [CoraFluor™ 1]

  • glicentin-related polypeptide
  • GLP1
  • GLP-1
  • glucagon-like peptide 1
  • GRPP

Background

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GCG