Species: Hu, Mu, Ma
Applications: ELISA, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu
Applications: IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Rt
Applications: ELISA
Description
Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.
Bioinformatics
| Entrez |
Human
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
2641 |
| Alternate Names |
- glicentin-related polypeptide
- GLP1
- glucagon-like peptide 1
- GRPP
|
Research Areas for GLP1
Find related products by research area and learn more about each of the different research areas below.
CancerGPCRSignal Transduction
![Immunohistochemistry GLP1 Antibody (970307) [Unconjugated]](http://images.novusbio.com/fullsize2/Glucagon_MAB12491_Immunohistochemistry_21041.jpg)
![Immunohistochemistry GLP1 Antibody (2622B) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab10473_human-glucagon-mab-clone-2622b-immunohistochemistry-3092020155750.jpg)
