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GLP-2R Antibody (413801) [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
413801
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

Order Details

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GLP-2R Antibody (413801) [HRP] Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human GLP-2R
Met1-Ile553
Accession # O95838
Specificity
Detects human GLP‑2R. Stains human GLP-2R transfectants but not irrelevant transfectants.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GLP2R
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for GLP-2R Antibody (413801) [HRP]

  • GLP-2 receptor
  • GLP2R
  • GLP-2R
  • GLP-2-R
  • glucagon-like peptide 2 receptor

Background

GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine. Activation of GLP2R signaling promotes expansion of the mucosal epithelium indirectly via activation of growth and anti-apoptotic pathways. GLP2R, through its ligand glucagon-like peptide 2 (GLP2), has been shown to prevent intestinal hypoplasia resulting from total parenteral nutrition. GLP2R has been reported primarily in the gastrointestinal tract, including intestine and stomach. In rats, GLPR2 has been shown in brain and lung. An EST has been isolated from a lung cancer library.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GLP2R