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FosB/G0S3 Antibody (83B1138) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
83B1138
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-56530AF350
Alexa Fluor 405
NB100-56530AF405
Alexa Fluor 488
NB100-56530AF488
Alexa Fluor 532
NB100-56530AF532
Alexa Fluor 594
NB100-56530AF594
Alexa Fluor 647
NB100-56530AF647
Alexa Fluor 700
NB100-56530AF700
Alexa Fluor 750
NB100-56530AF750
Biotin
NB100-56530B
CoraFluor 1
NB100-56530CL1
DyLight 350
NB100-56530UV
DyLight 405
NB100-56530V
DyLight 488
NB100-56530G
DyLight 550
NB100-56530R
DyLight 594
NB100-56530DL594
DyLight 650
NB100-56530C
DyLight 680
NB100-56530FR
DyLight 755
NB100-56530IR
FITC
NB100-56530F
HRP
NB100-56530H
Janelia Fluor 525
NB100-56530JF525
Janelia Fluor 549
NB100-56530JF549
Janelia Fluor 646
NB100-56530JF646
Unconjugated
NB100-56530
mFluor Violet 450 SE
NB100-56530MFV450
mFluor Violet 500 SE
NB100-56530MFV500
mFluor Violet 610 SE
NB100-56530MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-56530
BSA Free
NB100-56530
BSA Free
NB100-56530SS
Azide Free
NBP2-33219
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FosB/G0S3 Antibody (83B1138) [Janelia Fluor® 669] Summary

Immunogen
This antibody was generated by immunizing mice with a synthetic peptide corresponding to amino acids 2-15 of human FosB.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FOSB
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for FosB/G0S3 Antibody (83B1138) [Janelia Fluor® 669]

  • activator protein 1
  • AP-1
  • DKFZp686C0818
  • FBJ murine osteosarcoma viral oncogene homolog B
  • FosB
  • G0S3
  • G0S3G0/G1 switch regulatory protein 3
  • GOS3
  • GOSB
  • MGC42291
  • oncogene FOS-B
  • protein fosB

Background

Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the 'leucine-zipper' motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NB100-56530JF669
FosB/G0S3 Antibody (83B1138) [Janelia Fluor® 669]
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Bioinformatics

Gene Symbol FOSB