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Fc epsilon RI Antibody (AER-37) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
AER-37
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin
Concentration
5 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Allophycocyanin
NBP1-43278APC
Allophycocyanin/Cy7
NBP1-43278APCCY7
DyLight 350
NBP1-43278UV
DyLight 405
NBP1-43278V
DyLight 488
NBP1-43278G
DyLight 680
NBP1-43278FR
DyLight 755
NBP1-43278IR
FITC
NBP1-43940-100tests
Janelia Fluor 549
NBP1-43278JF549
Janelia Fluor 646
NBP1-43278JF646
PE
NBP1-43278PE
PE/Atto594
NBP1-43278PEATT594
PE/Cy5.5
NBP1-43278PECY55
PE/Cy7
NBP1-43278PECY7
PerCP
NBP1-43278PCP
Unconjugated
NBP1-43278-0.1mg
mFluor Violet 450 SE
NBP1-43278MFV450
mFluor Violet 500 SE
NBP1-43278MFV500
mFluor Violet 610 SE
NBP1-43278MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-43278-0.1mg
BSA Free
NBP1-43278-0.1mg
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Fc epsilon RI Antibody (AER-37) [Biotin] Summary

Immunogen
The immunogen for this antibody was FceRI alpha.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FCER1A
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
The AER-37 antibody has been tested by flow cytometric analysis of peripheral blood leukocytes. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
Readout System

Reactivity Notes

Use in Human reported in scientific literature (PMID:33741501).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2) with 0.1% gelatin
Preservative
0.09% Sodium Azide
Concentration
5 mg/ml
Purity
Protein A or G purified

Alternate Names for Fc epsilon RI Antibody (AER-37) [Biotin]

  • alpha polypeptide
  • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
  • Fc-epsilon RI-alpha
  • FcERI
  • high affinity immunoglobulin epsilon receptor alpha-subunit
  • high affinity immunoglobulin epsilon receptor subunit alpha
  • high-affinity, of mast cells, alpha polypeptide

Background

The AER-37 monoclonal antibody reacts with the Fc epsilon RI alpha subunit, an IgE-binding subunit lacking signal-transducing ability. Fc epsilon RI alpha is expressed on mast and basophil cells and is upregulated by the presence of IgE. Fc epsilon RI alpha forms a tetrameric complex with one beta and two gamma subunits. The beta and gamma subunits possess immunoreceptor tyrosine-based activation motifs (ITAM). The Fc epsilon RI complex plays an important role in triggering IgE-mediated allergic reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FCER1A