EVC2 Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: EVC2 Antibody [NBP2-47467] - Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
Immunohistochemistry: EVC2 Antibody [NBP2-47467] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubule.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

EVC2 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: KRESPITHRLYGDISREVQGTSENGVIFQKCALVSGSSEAQTARIWLLVNNTKTTSSANLSELLLLDSIAGLTIWDSVGNRTSEGFQAFSKKFLQV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EVC2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
EVC2 Protein (NBP2-47467PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for EVC2 Antibody

  • Ellis van Creveld syndrome 2
  • EVC2
  • LBN
  • LBNlimbin
  • Limbin
  • WAD

Background

The EVC2 gene encodes a protein that functions in bone formation and skeletal development. Mutations in this gene, as wellas in a neighboring gene that lies in a head-to-head configuration, cause Ellis-van Creveld syndrome, an autosomalrecessive skeletal dysp

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

ICC/IF Video Protocol

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Bioinformatics

Gene Symbol EVC2