ER alpha/NR3A1 Antibody (H4624) [Unconjugated] Summary
Immunogen
Recombinant human ER alpha/NR3A1 aa 2-180
Specificity
This antibody specifically recognizes human ER alpha and cross-reacts with mouse
and rat ER alpha. This antibody does not recognize human ER beta. Not yet tested in
other species.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
ESR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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This antibody is stable for greater than six months when held at -20 °C in a
manual defrost freezer or at -70 °C. Upon thawing, the antibody can be
stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid
repeated freeze-thaw cycles.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for ER alpha/NR3A1 Antibody (H4624) [Unconjugated]
Estrogen Receptor alpha (ER alpha, ER; NR3A1) is a member of the Steroid
Receptor family. The natural ligand for ER is the classic estrogenic compound
17 beta -estradiol. ER alpha is expressed in a wide variety of tissues such as bones,
uterus, bladder, ovary, prostate, testis, epididymis, kidney, breast, heart,
vessel wall, pituitary and hypothalamus. ER has a variety of central
physiological roles, including those involved in maintenance of the
reproductive, cardiovascular, musculoskeletal and central nervous systems.
ER alpha has been shown to form homodimers as well as heterodimers with ER beta.
Both ER alpha and ER beta can give rise to numerous isoforms.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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