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DPYD Antibody (SR1055)

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Western Blot: DPYD Antibody (SR1055) [NBP3-22329] - Western blot analysis using NBP3-22329 in HeLa cell lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
SR1055
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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DPYD Antibody (SR1055) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthesized peptide derived from human DPYD (Uniprot #: Q12882)
Specificity
Detects endogenous levels of total DPYD
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
DPYD
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:2000
Theoretical MW
110 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl, 50% glycerol.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for DPYD Antibody (SR1055)

  • DHP
  • DHPDHASE
  • dihydropyrimidine dehydrogenase [NADP+]
  • dihydropyrimidine dehydrogenase
  • Dihydrothymine dehydrogenase
  • Dihydrouracil dehydrogenase
  • DPDMGC132008
  • EC 1.3.1.2
  • MGC70799

Background

DPYD is encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for DPYD Antibody (NBP3-22329) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DPYD