DPYD Antibody (SR1055) Summary
Additional Information |
Recombinant Monoclonal Antibody |
Immunogen |
A synthesized peptide derived from human DPYD (Uniprot #: Q12882) |
Specificity |
Detects endogenous levels of total DPYD |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
DPYD |
Purity |
Affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry
- Immunocytochemistry/ Immunofluorescence 1:50-1:200
- Immunohistochemistry 1:50-1:200
- Western Blot 1:500-1:2000
|
Theoretical MW |
110 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS, pH 7.4, 150mM NaCl, 50% glycerol. |
Preservative |
0.02% Sodium Azide |
Purity |
Affinity purified |
Alternate Names for DPYD Antibody (SR1055)
Background
DPYD is encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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