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DNA Ligase I Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-97831AF350
Alexa Fluor 405
NBP2-97831AF405
Alexa Fluor 488
NBP2-97831AF488
Alexa Fluor 532
NBP2-97831AF532
Alexa Fluor 594
NBP2-97831AF594
Alexa Fluor 647
NBP2-97831AF647
Alexa Fluor 700
NBP2-97831AF700
Alexa Fluor 750
NBP2-97831AF750
Allophycocyanin
NBP2-97831APC
Biotin
NBP2-97831B
CoraFluor 1
NBP2-97831CL1
DyLight 350
NBP2-97831UV
DyLight 405
NBP2-97831V
DyLight 488
NBP2-97831G
DyLight 550
NBP2-97831R
DyLight 594
NBP2-97831DL594
DyLight 650
NBP2-97831C
DyLight 680
NBP2-97831FR
DyLight 755
NBP2-97831IR
FITC
NBP2-97831F
HRP
NBP2-97831H
Janelia Fluor 525
NBP2-97831JF525
Janelia Fluor 549
NBP2-97831JF549
Janelia Fluor 585
NBP2-97831JF585
Janelia Fluor 635
NBP2-97831JF635
Janelia Fluor 669
NBP2-97831JF669
PE
NBP2-97831PE
PerCP
NBP2-97831PCP
Unconjugated
NBP2-97831-100ul
mFluor Violet 450 SE
NBP2-97831MFV450
mFluor Violet 500 SE
NBP2-97831MFV500
mFluor Violet 610 SE
NBP2-97831MFV610
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DNA Ligase I Antibody [Janelia Fluor® 646] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human DNA Ligase I fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
LIG1
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DNA Ligase I Antibody [Janelia Fluor® 646]

  • DNA ligase 1
  • DNA Ligase I
  • EC 6.5.1.1
  • ligase I, DNA, ATP-dependent
  • MGC117397
  • MGC130025
  • Polydeoxyribonucleotide synthase [ATP] 1
  • polydeoxyribonucleotide synthase ATP 1

Background

DNA ligase 1 catalyzes the joining of double-stranded DNA ends during replication, recombination, and repair. Structurally, DNA ligase 1 is toroidal and encircles nicked DNA substrates. The 9-1-1 complex, a DNA damage checkpoint complex, has been reported to associate with DNA ligase 1 and stimulate ligase activity. Mutations in DNA ligase 1 result in immunodeficiency and increased sensitivity to DNA-damaging agents.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DNA Ligase I
Antibody [Janelia Flu ...
NBP2-97831JF646
DNA Ligase I Antibody [Janelia Fluor® 646]
Species: Hu
Applications: IHC

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Using PCNA as an Antibody Marker
PCNA antibodies are useful biomarkers in DNA repair studies. PCNA is one of several proteins essential for the completion of nucleotide excision repair, a multi-stage process involving 20 - 30 proteins, and an important factor in repairing damage and ...  Read full blog post.
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Bioinformatics

Gene Symbol LIG1