Derlin 1 Antibody Blocking Peptide Summary
Description |
A DERL1 antibody blocking peptide. |
Specificity |
This peptide is specific for NB100-448 only. |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
DERL1 |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NB100-448. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -80C. Avoid freeze-thaw cycles. |
Buffer |
Peptide dissolved in dH2O. Contains no BSA. |
Preservative |
No Preservative |
Concentration |
1.0 mg/ml |
Alternate Names for Derlin 1 Antibody Blocking Peptide
Background
Degradation in Endoplasmic Reticulum protein 1 (Derlin1) is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate degradative pathways within the cell. Specifically, Derlin-1 is thought to form a channel to allow retrotranslocation of misfolded proteins into the cytosol where they may be ubiquitinated and degraded by the proteasome.
Derlin 1 antibodies will serve as useful tools for protein degradation studies and for research on certian types of cancers.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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