Orthogonal Strategies: Immunohistochemistry-Paraffin: Decorin Antibody [NBP1-84970] - Staining in human ovary and cerebral cortex tissues using anti-DCN antibody. Corresponding DCN RNA-seq data are presented for ...read more
Western Blot: Decorin Antibody [NBP1-84970] - Analysis in control (vector only transfected HEK293T lysate) and DCN over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Western Blot: Decorin Antibody [NBP1-84970] - Analysis in human cell line U-2197.
Immunohistochemistry-Paraffin: Decorin Antibody [NBP1-84970] - Staining of human cerebral cortex shows low expression as expected.
Immunohistochemistry-Paraffin: Decorin Antibody [NBP1-84970] - Staining of human ovary shows high expression.
This antibody was developed against Recombinant Protein corresponding to amino acids: TNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQY
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DCN
Purity
Immunogen affinity purified
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Human reactivity reported in scientific literature (PMID: 24634138).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for Decorin Antibody
Bone proteoglycan II
CSCD
DCN
decorin proteoglycan
Decorin
dermatan sulphate proteoglycans II
DSPG2
PG40
PGII
PG-II
PGS2
PG-S2
proteoglycan core protein
SLRR1B
SLRR1BPGS2
small leucine-rich protein 1B
Background
Decorin is encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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