Claudin-12 Antibody (393314) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
393314
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 549

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Claudin-12 Antibody (393314) [Janelia Fluor® 549] Summary

Immunogen
HEK293 human embryonic kidney cell line transfected with human Claudin-12
Met1-Thr244
Accession # NP_036261
Specificity
Detects human Claudin-12. Stains human Claudin-12 transfectants but not irrelevant transfectants.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CLDN12
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Claudin-12 Antibody (393314) [Janelia Fluor® 549]

  • claudin 12
  • Claudin12
  • Claudin-12
  • CLDN12

Background

Claudins, such as CLDN12, are components of epithelial cell tight junctions. Tight junctions regulate movement ofsolutes and ions through the paracellular space and prevent mixing of proteins and lipids in the outer leaflet of theapical and basolateral plasma membrane domains (Acharya et al., 2004).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CLDN12