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Human CD41/CD61 ELISA Kit (Colorimetric)

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ELISA: Human CD41/CD61 ELISA Kit (Colorimetric) [NBP2-60471] - Standard curve.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Plasma, Cell Culture
Standard Curve Range
0.039 - 160 ng/mL (example only; lot dependent)
Sensitivity
0.013 ng/ml (example only; lot dependent)

Order Details

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Human CD41/CD61 ELISA Kit (Colorimetric) Summary

Description
This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Standard Curve Range
0.039 - 160 ng/mL (example only; lot dependent)
Sensitivity
0.013 ng/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Inter-Assay
CV% < 11.3% (example only; lot dependent)
Intra-Assay
CV% < 5.8% (example only; lot dependent)
Spike Recovery
87 - 115% (example only; lot dependent)
Kit Type
ELISA Kit (Colorimetric)
Gene
ITGA2B

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Alternate Names for Human CD41/CD61 ELISA Kit (Colorimetric)

  • CD41 antigen
  • CD41
  • CD41BHPA3
  • GP2Bintegrin alpha-IIb
  • GPalpha IIb
  • GPIIb
  • GTA
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
  • ITGAB
  • platelet fibrinogen receptor, alpha subunit
  • Platelet membrane glycoprotein IIb
  • platelet-specific antigen BAK

Background

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol ITGA2B