Caveolin-3 Antibody Summary
Immunogen |
Peptide with sequence EHTDLEAQIVKDIH-C corresponding to N-Terminus according to NP_203123.1. |
Epitope |
N Terminus |
Marker |
Muscle Specific Caveolae Marker, T-tubule Marker |
Specificity |
Reported variants represent identical protein (NP_001225.1; NP_203123.1). |
Predicted Species |
Canine (100%), Bovine (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
CAV3 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 3 - 5 ug/mL
- Immunohistochemistry-Paraffin 3 - 5 ug/mL
- Peptide ELISA Detection limit 1:4000
- Western Blot 0.1 - 0.3 ug/mL
|
Application Notes |
WB: Approx. 23 kDa band observed in human, mouse and rat heart lysates and 20 kDa band in porcine heart and skeletal muscle lysates (calculated MW of 17.3 kDa band according to NP_203123.1). IHC-P: Human skeletal muscle shows peripheral staining of fibres. |
Publications |
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Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
Preservative |
0.02% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for Caveolin-3 Antibody
Background
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for Caveolin-3 Antibody (NBP1-28917)(2)
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