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CARD14 Antibody [DyLight 650]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

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CARD14 Antibody [DyLight 650] Summary

Immunogen
CARMA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human CARMA2. The immunogen is located within the last 50 amino acids of CARMA2. Amino Acid Squence: DEQKKVVWTEQSPR
Specificity
CARD14 antibody is human specific. At least three isoforms of CARD14 are known to exist; this antibody will only detect isoform 1. CARD14 antibody is predicted not to cross-react with other CARMA proteins.
Predicted Species
Mouse (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CARD14
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CARD14 Antibody [DyLight 650]

  • bcl10-interacting maguk protein 2
  • BIMP2
  • CARD-containing MAGUK protein 2
  • card-maguk protein 2
  • Carma 2
  • CARMA2CARD-containing MAGUK 2 protein
  • caspase recruitment domain family, member 14
  • caspase recruitment domain-containing protein 14

Background

The protein encoded by the CARD14 gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class ofproteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions ofthe plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying acharacteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure withCARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein knownto function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this proteinactivated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encodingdistinct isoforms have been reported. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for CARD14 Antibody (NBP2-81901C) (0)

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Secondary Antibodies

 

Isotype Controls

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Blogs on CARD14.

CARD14: The First Gene to be Linked to Psoriasis
Psoriasis is an autoimmune disease affects 3% of the United Kingdom's population and 7.5 million people in the United States are affected. This disease causes plaque formation on the skin due to an increased rate of skin cell growth. Psoriasis is trig...  Read full blog post.

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Bioinformatics

Gene Symbol CARD14