Cannabinoid R1/CB1/CNR1 Antibody (GFB-024) - Humanized

Images

 
Human CB1 / CNR1 EGFP HEK293 Cell Line were stained with Cannabinoid R1/CB1/CNR1 Antibody (GFB-024) - Humanized and negative control protein respectively, washed and then followed by APC and analyzed with FACS, ...read more
Human CB1 EGFP CHOS cells were stained with Cannabinoid R1/CB1/CNR1 Antibody (GFB-024) - Humanized and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=2.363 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
GFB-024
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Cannabinoid R1/CB1/CNR1 Antibody (GFB-024) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
CB1 / CNR1
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
CNR1
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Cannabinoid R1/CB1/CNR1 Antibody (GFB-024) - Humanized

  • CANN6
  • CANN6CB1R
  • Cannabinoid R1
  • cannabinoid receptor 1 (brain)
  • CannabinoidR1
  • CB1
  • CB1A
  • CB1K5
  • CB1R
  • CB-R
  • CB-RCB1cannabinoid receptor 1
  • central cannabinoid receptor
  • CNR
  • CNR1
  • SKR6R

Background

CB1 Cannabinoid receptor is associated with the regulation of cognition, memory, and motor activity. The CB1 receptor mediates cannabinoid-induced CNS effects and the addictive behavior experienced by users of marijuana. Three splice variants that are produced by alternative splicing have been identified for this gene. CB1 has been reported primarily in the brain and, to a lower extent, in peripheral tissues including adrenal, heart, lung, prostate, uterus, ovary, testis, bone marrow, thymus, and tonsil. ESTs have been isolated from brain, embryo, heart/melanocyte/uterus, lung, placenta, testis, tonsil, and vessel libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CNR1
Uniprot