CA125/MUC16 Antibody (986808) [Biotin] Summary
Immunogen |
Chinese hamster ovary cell line CHO-derived recombinant human CA125/MUC-16 Met13360-Gln14347 (Met13472Thr & Gln13957Lys) Accession # NP_078966.2 |
Specificity |
Detects human CA125/MUC-16 in direct ELISAs. |
Isotype |
IgG2a |
Clonality |
Monoclonal |
Host |
Mouse |
Purity |
Protein A or G purified from ascites |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Flow Cytometry
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified from ascites |
Alternate Names for CA125/MUC16 Antibody (986808) [Biotin]
Background
MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for CA125/MUC16 Antibody (FAB5609B) (0)
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