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ATR Antibody [DyLight 755]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 755

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-98982AF350
Alexa Fluor 405
NBP2-98982AF405
Alexa Fluor 488
NBP2-98982AF488
Alexa Fluor 532
NBP2-98982AF532
Alexa Fluor 594
NBP2-98982AF594
Alexa Fluor 647
NBP2-98982AF647
Alexa Fluor 700
NBP2-98982AF700
Alexa Fluor 750
NBP2-98982AF750
Allophycocyanin
NBP2-98982APC
Biotin
NBP2-98982B
CoraFluor 1
NBP2-98982CL1
DyLight 350
NBP2-98982UV
DyLight 405
NBP2-98982V
DyLight 488
NBP2-98982G
DyLight 550
NBP2-98982R
DyLight 594
NBP2-98982DL594
DyLight 650
NBP2-98982C
DyLight 680
NBP2-98982FR
FITC
NBP2-98982F
HRP
NBP2-98982H
Janelia Fluor 525
NBP2-98982JF525
Janelia Fluor 549
NBP2-98982JF549
Janelia Fluor 585
NBP2-98982JF585
Janelia Fluor 635
NBP2-98982JF635
Janelia Fluor 646
NBP2-98982JF646
Janelia Fluor 669
NBP2-98982JF669
PE
NBP2-98982PE
PerCP
NBP2-98982PCP
Unconjugated
NBP2-98982-100ul
mFluor Violet 450 SE
NBP2-98982MFV450
mFluor Violet 500 SE
NBP2-98982MFV500
mFluor Violet 610 SE
NBP2-98982MFV610
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ATR Antibody [DyLight 755] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human ATR.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATR
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ATR Antibody [DyLight 755]

  • ataxia telangiectasia and Rad3 related
  • Ataxia telangiectasia and Rad3-related protein
  • ATR
  • EC 2.7.11.1
  • FRAP-related protein 1
  • FRP1
  • FRP1FRAP-related protein-1
  • MEC1
  • protein kinase ATR
  • Rad3 related protein
  • SCKL1
  • SCKLMEC1, mitosis entry checkpoint 1, homolog
  • serine/threonine-protein kinase ATR

Background

Ataxia Telangiectasia Mutated (ATM) and Rad3- related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP2-98982IR

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Blogs on ATR.

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Further unraveling the role of gamma H2AX in DNA damage response
Our genome experiences a moderate amount of DNA damage in our cells on a daily basis.  This DNA damage can be in response to external environmental factors, or be a result of our internal metabolic processes going awry.  While normal rates of DNA ...  Read full blog post.
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The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage.  DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m...  Read full blog post.
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Bioinformatics

Gene Symbol ATR