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ATR Antibody [Janelia Fluor® 646]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-323AF350
Alexa Fluor 405
NB100-323AF405
Alexa Fluor 488
NB100-323AF488
Alexa Fluor 532
NB100-323AF532
Alexa Fluor 594
NB100-323AF594
Alexa Fluor 647
NB100-323AF647
Alexa Fluor 700
NB100-323AF700
Alexa Fluor 750
NB100-323AF750
Allophycocyanin
NB100-323APC
Biotin
NB100-323B
CoraFluor 1
NB100-323CL1
DyLight 350
NB100-323UV
DyLight 405
NB100-323V
DyLight 488
NB100-323G
DyLight 550
NB100-323R
DyLight 594
NB100-323DL594
DyLight 650
NB100-323C
DyLight 680
NB100-323FR
DyLight 755
NB100-323IR
FITC
NB100-323F
HRP
NB100-323H
Janelia Fluor 525
NB100-323JF525
Janelia Fluor 549
NB100-323JF549
Janelia Fluor 585
NB100-323JF585
Janelia Fluor 635
NB100-323JF635
Janelia Fluor 669
NB100-323JF669
PE
NB100-323PE
PerCP
NB100-323PCP
Unconjugated
NB100-323
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ATR Antibody [Janelia Fluor® 646] Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residues 400 and 450 of human Ataxia Telangiectasia and Rad3-related using the numbering given in entry NP_001175.1 (GeneID 545).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ATR
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID:24356582).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ATR Antibody [Janelia Fluor® 646]

  • ataxia telangiectasia and Rad3 related
  • Ataxia telangiectasia and Rad3-related protein
  • ATR
  • EC 2.7.11.1
  • FRAP-related protein 1
  • FRP1
  • FRP1FRAP-related protein-1
  • MEC1
  • protein kinase ATR
  • Rad3 related protein
  • SCKL1
  • SCKLMEC1, mitosis entry checkpoint 1, homolog
  • serine/threonine-protein kinase ATR

Background

Ataxia Telangiectasia Mutated (ATM) and Rad3- related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage.  DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m...  Read full blog post.
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Bioinformatics

Gene Symbol ATR