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Adenylate Cyclase 6 Antibody

Images

 
Western Blot: Adenylate Cyclase 6 Antibody [NBP3-12233] - 1:500 antibody dilution in DiluObuffer. Apparent NW is 130 kDa.
Immunohistochemistry-Paraffin: Adenylate Cyclase 6 Antibody [NBP3-12233] - Rat heart.1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.
Immunohistochemistry-Paraffin: Adenylate Cyclase 6 Antibody [NBP3-12233] - Rat Heart. 1:100 dilution in IHC Blocking buffer. DAB (brown) staining and hematoxylin QS (blue) counterstain. 10X magnification.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Adenylate Cyclase 6 Antibody Summary

Immunogen
Synthetic peptide corresponding to N-terminal amino acids 13-27 of rat Particulate Adenylyl Cyclase 6 protein. Peptide was covalently modified and conjugated to KLH. Sequence: DERKTAWGERNGQKR
Clonality
Polyclonal
Host
Rabbit
Gene
ADCY6
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:10000
  • Immunocytochemistry/ Immunofluorescence 1:100-1:200
  • Immunohistochemistry 1:100-1:200
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot 1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Adenylate Cyclase 6 Antibody

  • AC6
  • ADCY6
  • Adenylate Cyclase 6
  • adenylate cyclase type 6
  • Adenylate cyclase type VI
  • Adenylyl cyclase 6
  • ATP pyrophosphate-lyase 6
  • Ca(2+)-inhibitable adenylyl cyclase
  • DKFZp779F075
  • EC 4.6.1.1
  • KIAA0422

Background

ADCY6, also known as Adenylate cyclase type 6, consists of a 1,168 amino acid long isoform that is 131 kDa and a shorter 1,115 amino acid isoform that is 125 kDa, and is involved in the encoding of a membrane-bound enzyme. This protein has also been shown to have interactions with ATXN1, GNAS, CHRNA7, RAF1, and ADCY1 in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY6 and cholera, ataxia, and adenoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADCY6