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ACSL6 Recombinant Protein Antigen

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Summary
Reactivity HuSpecies Glossary
Applications AC

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ACSL6 Recombinant Protein Antigen Summary

Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human ACSL6.

Source: E. coli

Amino Acid Sequence: RYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADF

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Source
E. coli
Protein/Peptide Type
Recombinant Protein Antigen
Gene
ACSL6
Purity
>80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

Dilutions
  • Antibody Competition 10 - 100 molar excess
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-89269.It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com
Theoretical MW
30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 1M Urea, pH 7.4.
Preservative
No Preservative
Purity
>80% by SDS-PAGE and Coomassie blue staining

Alternate Names for ACSL6 Recombinant Protein Antigen

  • ACS2long-chain 6
  • acyl-CoA synthetase long-chain family member 6
  • EC 6.2.1
  • EC 6.2.1.3
  • FLJ16173
  • LACS 6
  • long fatty acyl-CoA synthetase 2
  • Long-chain acyl-CoA synthetase 6
  • long-chain-fatty-acid--CoA ligase 6

Background

Long-chain-fatty-acid--CoA ligase 6, or ACSL6, is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. These proteins play an important role in both the synthesis of cellular lipids and in beta-oxidation degradation. Like other isozymes of this family, ALCS6 converts free long-chain fatty acids into fatty acyl-CoA esters. Specifially, ACSL6 is critical for fatty acid metabolism in the brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.

ACSL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol ACSL6