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Acetylcholinesterase/ACHE Antibody [Janelia Fluor® 585]

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB600-911JF585
    • Availability
      Product Discontinued

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Acetylcholinesterase/ACHE Antibody [Janelia Fluor® 585] Summary

Immunogen
Acetylcholinesterase/ACHE [Bovine Erythrocytes] (Uniprot: P23795)
Localization
Cell Membrane and Secreted
Marker
Early Neuronal Development Marker
Specificity
Cross reactivity against Acetylcholinesterase/ACHE from other sources is unknown.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ACHE
Purity
Multi-step
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Cross reactivity against Acetylcholinesterase/ACHE from other sources is unknown.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Multi-step

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Acetylcholinesterase/ACHE Antibody [Janelia Fluor® 585]

  • acetylcholinesterase (Yt blood group)
  • Acetylcholinesterase
  • ACHE
  • apoptosis-related acetylcholinesterase
  • ARACHE
  • EC 3.1.1
  • EC 3.1.1.7
  • N-ACHE
  • Yt blood group
  • YT

Background

Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ACHE