Acetylcholinesterase/ACHE Antibody [Janelia Fluor® 585] Summary
Immunogen |
Acetylcholinesterase/ACHE [Bovine Erythrocytes] (Uniprot: P23795) |
Localization |
Cell Membrane and Secreted |
Marker |
Early Neuronal Development Marker |
Specificity |
Cross reactivity against Acetylcholinesterase/ACHE from other sources is unknown. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
ACHE |
Purity |
Multi-step |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Immunoprecipitation
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Reactivity Notes
Cross reactivity against Acetylcholinesterase/ACHE from other sources is unknown.
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Purity |
Multi-step |
Notes
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
Alternate Names for Acetylcholinesterase/ACHE Antibody [Janelia Fluor® 585]
Background
Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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