5-HT2C Antibody (496214) [Phycoerythrin] Summary
Immunogen |
NS0 mouse myeloma cell line transfected with human 5HT2C |
Specificity |
Detects human 5HT2C in direct ELISAs. |
Source |
N/A |
Isotype |
IgG2a |
Clonality |
Monoclonal |
Host |
Mouse |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 10 uL/10^6 cells
|
Packaging, Storage & Formulations
Storage |
Protect from light. Do not freeze.- 12 months from date of receipt, 2 to 8 °C as supplied.
|
Buffer |
Supplied in a saline solution containing BSA and Sodium Azide. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for 5-HT2C Antibody (496214) [Phycoerythrin]
Background
5-HT2C is a 45 kDa 7TM receptor that belongs to the G-protein coupled
receptor #1 family. It binds serotonin and is neuronally expressed in
the limbic system of the brain. The release of dopamine due to 5-HT2C
ligation regulates mood, appetite, and motivation. 5-HT2C is an
important pharmacologic target in the treatment of psychosis,
schizophrenia, depression, anxiety, and migrane headaches. Multiple
isoforms of 5-HT2C can be generated by RNA editing. Human 5-HT2C shares
89% aa sequence identity with mouse and rat 5-HT2C.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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