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5-HT2C Antibody (496214) [Allophycocyanin]

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HEK293 human embryonic kidney cell line transfected with human 5-HT2C and eGFP was stained with either (A) Mouse Anti-Human 5-HT2C APC-conjugated Monoclonal Antibody (Catalog # FAB5764A) or (B) Mouse ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
496214
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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5-HT2C Antibody (496214) [Allophycocyanin] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human 5-HT2C
Accession # P28335
Specificity
Detects human 5-HT2C in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
HTR2C
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for 5-HT2C Antibody (496214) [Allophycocyanin]

  • 5-HT1C
  • 5-HT-1C
  • 5HT2C
  • 5-HT2C
  • 5-HT-2C
  • 5-HT2C5-hydroxytryptamine receptor 1C
  • 5-HTR2C
  • 5-hydroxytryptamine (serotonin) receptor 2C
  • 5-hydroxytryptamine receptor 2C
  • HTR1C
  • HTR2C
  • serotonin 5-HT-2C receptor
  • Serotonin Receptor 2C

Background

5-HT2C is a 45 kDa 7TM receptor that belongs to the G-protein coupled receptor #1 family. It binds serotonin and is neuronally expressed in the limbic system of the brain. The release of dopamine due to 5-HT2C ligation regulates mood, appetite, and motivation. 5-HT2C is an important pharmacologic target in the treatment of psychosis, schizophrenia, depression, anxiety, and migrane headaches. Multiple isoforms of 5-HT2C can be generated by RNA editing. Human 5-HT2C shares 89% aa sequence identity with mouse and rat 5-HT2C.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HTR2C
Uniprot