p70 S6 Kinase/S6K Products

Description

S6K encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

Bioinformatics

Entrez	361696 Rat 58988 Mouse 6198 Human 72508 Mouse 83840 Rat
Uniprot	M60725 Human NM_003161 Human NP_003152 Human NP_003152.1 Human P23443 Human Q9UBS0 Human
Product By Gene ID	6198
Alternate Names	EC 2.7.11 EC 2.7.11.1 p70 ribosomal S6 kinase alpha p70 S6 kinase alpha p70 S6 kinase, alpha 1,70 kDa ribosomal protein S6 kinase 1 p70 S6 kinase, alpha 2 p70 S6KA p70 S6K-alpha p70(S6K)-alpha p70-alpha p70-S6K P70S6K1 PS6K ribosomal protein S6 kinase beta-1 Ribosomal protein S6 kinase I ribosomal protein S6 kinase, 70kD, polypeptide 1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 S6K S6K1p70-S6K 1 S6K-beta-1 serine/threonine kinase 14 alpha Serine/threonine-protein kinase 14A STK14A

Research Areas for p70 S6 Kinase/S6K

Find related products by research area and learn more about each of the different research areas below.

Autophagy
Cancer
mTOR Pathway
Phospho-Specific
Protein Kinase
Signal Transduction

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S6K - a serine/threonine kinase with diverse roles in cell survival and cell cycle progression S6K is a serine/threonine kinase that is a member of the ribosomal S6 kinase (RSK) family. S6K exists in two main isoforms, S6K1 and S6K2, which can also be alternatively spliced to produce different splice forms. S6K1 has two major splicing produ...    Read more.

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