Species: Hu, Pm, Ch(-), Mu(-), Rt(-)
Applications: Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNAdependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
2547 |
| Alternate Names |
- 5'-deoxyribose-5-phosphate lyase Ku70
- 5'-dRP lyase Ku70
- 70 kDa subunit of Ku antigen
- ATP-dependent DNA helicase 2 subunit 1
- ATP-dependent DNA helicase II 70 kDa subunit
- CTC box binding factor 75 kDa subunit
- CTC box-binding factor 75 kDa subunit
- CTC75
- CTCBF
- D22S731
- EC 3.6.4.-
- EC 4.2.99.-
- G22P1Ku70
- Ku autoantigen p70 subunit
- Ku autoantigen, 70kDa
- KU70
- ML8,70 kDa subunit
- thyroid-lupus autoantigen p70
- Thyroid-lupus autoantigen
- TLAAD22S671
- X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6
- X-ray repair cross-complementing protein 6
|
