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Recurrent Adult Acute Myeloid Leukemia: Disease Bioinformatics

Recurrent Acute Myeloid Leukemia is a clonal disorder caused by malignant transformation of a bone marrow-derived, self-renewing stem cell or progenitor, in which the patient enters remission and relapses. This leads to a decreased rate of self-destruction and aberrant differentiation causing an accumulation in the organs and bone marrow by these myeloid cells. The development of Acute Myeloid Leukemia has been associated with many predisposition syndromes that are caused by chromosomal imbalances, DNA repair defects, altered protein synthesis and altered cytokine receptors or signal transduction pathways.

Top Research Reagents

We have 1675 products for the study of Recurrent Adult Acute Myeloid Leukemia that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

MSH3 Antibody (CL14059)
NBP3-24587
Staining of human breast cancer shows moderate to strong nuclear positivity in tumor cells.Western blot analysis in human cell line U-251 MG.

Mouse Monoclonal
Species Human
Applications WB, ICC/IF, IHC

NFkB p105/p50 Antibody (2J10D7) - BSA Free
NB100-56583
Western Blot: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - Analysis of p50 in HeLa lysate in the A) absence and B) presence of immunizing peptide using p50 antibody at 5 ug/ml.Immunohistochemistry-Paraffin: NFkB p105/p50 Antibody (2J10D7) [NB100-56583] - IHC-P of rabbit aorta using NB100-56583. Secondary antibody: anti-mouse histofine ( Nisherei Bioscience Inc. ref: 414131F). Development: DAB (Dako ref: K346811-2) and counterstained with Hematoxylin. Submitted via verified customer review

Mouse Monoclonal
Species Human, Rat, Rabbit
Applications WB, Flow, IHC

     1 Review

5 Publications
MVP Antibody
NBP1-82820
Western Blot: MVP Antibody [NBP1-82820] - Analysis in human cell lines A-549 and HEK293. Corresponding RNA-seq data are presented for the same cell lines. Loading control: Anti-HDAC1.Immunocytochemistry/Immunofluorescence: MVP Antibody [NBP1-82820] - Staining of human cell line U-251 MG shows localization to cytosol. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, Simple Western, ICC/IF

PGPEP-1 Antibody
AF6278
Western blot shows lysates of LNCaP human prostate cancer cell line, JAR human choriocarcinoma cell line, NTera-2 human testicular embryonic carcinoma cell line, Neuro-2A mouse neuroblastoma cell line, and human brain (cortex) tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human PGPEP-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6278) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # <a class=

Sheep Polyclonal
Species Human, Mouse
Applications WB

G-CSF Antibody (67604) [Unconjugated]
MAB414
Recombinant Mouse G-CSF (Catalog # <a class=

Rat Monoclonal
Species Mouse
Applications WB, ELISA(Cap), ELISA(Det)

60 Publications
LRP-1 Antibody (A2Mr alpha-2)
NB100-64808
Immunohistochemistry: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2 followed by the Histar detection system. High power.Immunohistochemistry: LRP-1 Antibody (A2Mr alpha-2) [NB100-64808] - Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD91 antibody, clone A2Mr alpha-2 followed by the Histar detection system. Low power.

Mouse Monoclonal
Species Human
Applications WB, ELISA, Flow

3 Publications
Siglec-3/CD33 Antibody (996810) [Unconjugated]
MAB11371
Western blot shows lysates of U937 human histiocytic lymphoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Siglec-3/CD33 Monoclonal Antibody (Catalog # MAB11371) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class=Siglec-3/CD33 was detected in immersion fixed U937 human histiocytic lymphoma cell line (left panel; positive stain) and MOLT-4 human acute lymphoblastic leukemia cell line (right panel; negative stain) using Mouse Anti-Human Siglec-3/CD33 Monoclonal Antibody (Catalog # MAB11371) at 8 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # <a class=

Mouse Monoclonal
Species Human
Applications WB, IHC, ICC

     1 Review

2 Publications
RPSA Antibody (RPSA/2699) - Azide and BSA Free
NBP2-79854
Western Blot: RPSA Antibody (RPSA/2699) - Azide and BSA Free [NBP2-79854] - Western Blot Analysis of human THP-1, U937, SK-BR3, and A431 cell lysates. RPSA Antibody (RPSA/2699).Immunocytochemistry/Immunofluorescence: RPSA Antibody (RPSA/2699) - Azide and BSA Free [NBP2-79854] - Immunofluorescent staining of paraformaldehyde-Raji cells using RPSA Antibody (RPSA/2699) followed by goat anti-Mouse IgG conjugated to CF488 (green). Nuclei are labeled with RedDot (red).

Mouse Monoclonal
Species Human
Applications WB, Flow, ICC/IF

MDMX Antibody
NB100-556
Western Blot: MDMX Antibody [NB100-556] - Detection of human HdmX/MDM4 by western blot. Samples: Whole cell lysate (50 ug) from Jurkat, HEK293T, and HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-HdmX/MDM4 antibody NB100-556 used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 75 seconds.Western Blot: MDMX Antibody [NB100-556] - Analysis using the Biotin conjugate of NB100-556. Detection of Jurkat (50, 15, and 5 ug). Antibody used at 1.0 ug/ml. Detection: Streptavidin-HRP and chemiluminescence with an exposure time of 30 seconds.

Rabbit Polyclonal
Species Human
Applications WB, IP

33 Publications
MRP1 Antibody (IU2H10) - BSA Free
NB400-156
Dual RNAscope ISH-IHC: MRP1 Antibody (IU2H10) [NB400-156] - Formalin-fixed paraffin-embedded tissue sections of human testis were probed for MRP1 mRNA (ACD RNAScope Probe, catalog # 435591; Fast Red chromogen, ACD catalog # 322360). Adjacent tissue section was processed for immunohistochemistry using mouse monoclonal (Novus Biologicals catalog # NB400-156) at 7ug/mL with overnight incubation at 4 degrees Celsius followed by incubation with anti-mouse IgG VisUCyte HRP Polymer Antibody (Catalog # VC001) and DAB chromogen (yellow-brown). Tissue was counterstained with hematoxylin (blue). Specific staining was localized to Leydig cells and seminiferous tubule cells.Immunocytochemistry/Immunofluorescence: MRP1 Antibody (IU2H10) [NB400-156] - The MRP-1 antibody was tested in HeLa cells at a 1:50 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue), respectively.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

17 Publications
PTP alpha/PTPRA Antibody
NBP3-14454
Immunohistochemistry: PTP alpha/PTPRA Antibody [NBP3-14454] - Immunohistochemistry of lung, non-small cell carcinoma,Immunohistochemistry-Paraffin: PTP alpha/PTPRA Antibody [NBP3-14454] - Immunohistochemistry of formalin-fixed, paraffin-embedded human skeletal muscle after heat-induced antigen retrieval.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P


Related Genes

Recurrent Adult Acute Myeloid Leukemia has been researched against:

Related Pathways

Recurrent Adult Acute Myeloid Leukemia has been linked to:

Related Diseases

Recurrent Adult Acute Myeloid Leukemia has been studied in relation to diseases such as:

Alternate Names

Recurrent Adult Acute Myeloid Leukemia is also known as Recurrent Adult Aml, Relapsed Adult Acute Myeloid Leukemia, Relapsed Adult Aml.