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Legionnaires' Disease: Disease Bioinformatics

Research of Legionnaires' Disease has been linked to Pneumonia, Legionellosis, Infective Disorder, Cross Infection, Community-acquired Infections. The study of Legionnaires' Disease has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Legionnaires' Disease include Virulence, Secretion, Pathogenesis, Phagocytosis, Transport. These pathways complement our catalog of research reagents for the study of Legionnaires' Disease including antibodies and ELISA kits against SPA, CASP1, CRP, FOXC2, HSPD1.

Top Research Reagents

We have 3621 products for the study of Legionnaires' Disease that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

C-Reactive Protein/CRP [HRP]
DCRP00B
N/A C-Reactive Protein/CRP [HRP]N/A C-Reactive Protein/CRP [HRP]


Species Human
Applications ELISA

150 Publications
IL-6 [HRP]
D6050B
N/A IL-6 [HRP]N/A IL-6 [HRP]


Species Human

776 Publications
PTPLA Overexpression Lysate
NBL1-14964
Western Blot: PTPLA Overexpression Lysate (Adult Normal) [NBL1-14964] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PTPLA.


Species Human
Applications WB

Caspase-1 Antibody (14F468) - BSA Free
NB100-56565
Simple Western lane view shows a specific band for Caspase 1 in 1.0 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.Activity of Casp1 in OHT-injured and normotensive control eyes. (A) Casp1 was detected by intraocular injection FLICA660-labeled substrate (green) in vivo 24 h after injury. Bright labeling (arrows) is evident in cells in the GCL and inner nuclear layer (INL) layers of the OHT-challenged retinas, a diffuse labeling of cell processes located in the IPL. Casp1 activity is diminished in Panx1-/- (Px1-/- OHT) retinas and WT retinas treated with probenecid (WT/Pbcd) at 12 h postinjury. Image collected and cropped by CiteAb from the following publication (https://www.frontiersin.org/article/10.3389/fnmol.2019.00036/full), licensed under a CC-BY license.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ICC/IF

72 Publications
HSP60 Antibody - BSA Free
NBP1-77397
Immunocytochemistry/Immunofluorescence: HSP60 Antibody [NBP1-77397] - HeLa cells were fixed in 4% paraformaldehyde for 10 minutes and permeabilized in 0.05% Triton X-100 in PBS for 5 minutes. The cells were incubated with HSP60 Antibody (NBP1-77397) at 1 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 100X objective and digitally deconvolved.Western Blot: HSP60 Antibody [NBP1-77397] - Analysis of extracts from HeLa and COS cells using NBP1-77397 Hsp60 antibody at 1:1000

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

     4 Reviews

6 Publications
FMN1 Antibody (4F4)
H00342184-M07
Western Blot: FMN1 Antibody (4F4) [H00342184-M07] - Analysis of FMN1 expression in Jurkat.Immunocytochemistry/Immunofluorescence: FMN1 Antibody (4F4) [H00342184-M07] - Analysis of monoclonal antibody to FMN1 on HeLa cell. Antibody concentration 10 ug/ml

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

CARD12 Antibody - BSA Free
NBP1-78979
Immunocytochemistry/Immunofluorescence: CARD12 Antibody [NBP1-78979] - The CARD12 antibody (NBP1-78979) was tested in HepG2 cells at a 1:250 dilution against Dylight 488 (Green). Alpha tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue), respectively.Immunohistochemistry: CARD12 Antibody [NBP1-78979] - IHC analysis of CARD12 in mouse lung using DAB with hematoxylin counterstain.

Rabbit Polyclonal
Species Human, Mouse
Applications Flow, IB, ICC/IF

2 Publications
SORBS1 Antibody
NBP1-86641
Immunohistochemistry-Paraffin: SORBS1 Antibody [NBP1-86641] - Staining of human cerebral cortex, colon, lymph node and testis using Anti-SORBS1 antibody NBP1-86641 (A) shows similar protein distribution across tissues to independent antibody NBP2-33383 (B).Western Blot: SORBS1 Antibody [NBP1-86641] - Analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1 and #2,. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
CAP1 Antibody
NBP1-86644
Western Blot: CAP1 Antibody [NBP1-86644] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)Immunocytochemistry/Immunofluorescence: CAP1 Antibody [NBP1-86644] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
Serpin B6 Antibody (OTI1C5)
NBP2-01650
Western Blot: Serpin B6 Antibody (1C5) [NBP2-01650] - Analysis of extracts (10ug) from 9 Human tissue by using anti-SERPINB6 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon)Immunohistochemistry-Paraffin: SerpinB6 Antibody (1C5) [NBP2-01650] - Staining of paraffin-embedded Human liver tissue using anti-SerpinB6 mouse monoclonal antibody.

Mouse Monoclonal
Species Human, Mouse, Monkey
Applications WB, Flow, IHC

1 Publication
Signal Peptide Peptidase Antibody
NBP2-32276
Western Blot: Signal Peptide Peptidase Antibody [NBP2-32276] - Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-SPP antibody NBP2-32276 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.Immunoprecipitation: Signal Peptide Peptidase Antibody [NBP2-32276] - Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) prepared using NETN buffer from HeLa cells. Antibodies: Affinity purified rabbit anti-SPP antibody NBP2-32276 used for IP at 6 ug per reaction. SPP was also immunoprecipitated by rabbit anti-SPP antibody BL16569. For blotting immunoprecipitated SPP, NBP2-32276 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Rabbit Polyclonal
Species Human
Applications WB, IP

FoxC2 Antibody
AF6989
FoxC2 was detected in immersion fixed frozen sections of mouse embryo (E15.5) using Sheep Anti-Mouse FoxC2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6989) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href=YAP and TAZ are required for the maintenance of LVs. The lymphatic vessels in the dorsal skin of E16.5 and E18.5 control and Lyve1-Cre;Yapf/f;Tazf/f embryos were analyzed by whole-mount immunohistochemistry. (A,B) LVs were observed in the collecting lymphatic vessels of E16.5 control and Lyve1-Cre;Yapf/f;Tazf/f embryos (arrows). (C,D) The migrating front of E16.5 control (C) and Lyve1-Cre;Yapf/f;Tazf/f (D) embryos appeared comparable. (E-G) At E18.5, the lymphatic vessels from the left and right sides have merged to form a network in control embryos (E). In contrast, huge gaps were observed in between the migrating fronts of E18.5 Lyve1-Cre;Yapf/f;Tazf/f embryos (F, magenta lines). The lymphatic vessels of mutant embryos were also dilated. The distance between the migrating fronts and the diameter of vessels are quantified in G. (H,I) LVs were observed in the collecting lymphatic vessels of E18.5 control embryos (H, yellow arrows). In contrast, the dilated lymphatic vessels of E18.5 Lyve1-Cre;Yapf/f;Tazf/f embryos lacked LVs (I). The various parameters of lymphatic vascular patterning were quantified and are plotted in G. n=4 embryos per each genotype. ****P<0.0001. Data are mean±s.e.m. Scale bars: 200 µm in A-D; 500 µm in E,F; 200 µm in H,I. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33060128), licensed under a CC-BY license. Not internally tested by R&D Systems.

Sheep Polyclonal
Species Mouse
Applications IHC

27 Publications
IFN-gamma [Unconjugated]
285-IF
Recombinant Human IFN-gamma (Catalog # 285-IF) has a molecular weight (MW) of 34.9 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).1 μg/lane of Recombinant Human IFN-gamma was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa.


Species Human
Applications BA

     2 Reviews

453 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

817 Publications
Transportin 1 Antibody (D45) - BSA Free
NB600-1397
Western Blot: Transportin 1 Antibody (D45) [NB600-1397] - Human lung cancer cell line usig lysates from HCC44 cell line. (N: Nuclear fraction, C: Cytoplasmic fraction). Image from verified customer review.Immunohistochemistry-Paraffin: Transportin 1 Antibody (D45) [NB600-1397] - IHC analysis of a formalin fixed paraffin embedded tissue section of human pancreas using Transportin 1 antibody (clone D45) at 1:200 dilution. The antibody generated specific nuclear and cytoplasmic signal of Transportin 1 protein in the glandular cells while the connective tissue was largely negative.

Mouse Monoclonal
Species Human, Mouse, Bovine
Applications WB, Flow, ICC/IF

     1 Review

8 Publications
MIPEP Antibody (OTI5E7)
NBP2-45861
Western Blot: MIPEP Antibody (OTI5E7) [NBP2-45861] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MIPEP.Immunohistochemistry: MIPEP Antibody (OTI5E7) [NBP2-45861] - Analysis of Carcinoma of Human thyroid tissue.

Mouse monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

BRD4 Antibody (BL-149-2H5)
NBP2-76393
Western Blot: BRD4 Antibody (BL-149-2H5) [NBP2-76393] - Detection of mouse BRD4 by WB of BW5147.3 lysate. Antibody: BRD4 Antibody (BL-149-2H5). Secondary: HRP-conjugated goat anti-rabbit IgG.Immunocytochemistry/Immunofluorescence: BRD4 Antibody (BL-149-2H5) [NBP2-76393] - Antibody: Rabbit anti-BRD4 recombinant monoclonal [BL-149-2H5] (NBP2-76393). Secondary: DyLight 550-conjugated goat anti-rabbit IgG. Counterstain: Phalloidin Alexa Fluor 488-conjugated (green).

Rabbit Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

Leucyl-cystinyl Aminopeptidase/LNPEP Antibody - BSA Free
NBP2-81854
Western Blot: Leucyl-cystinyl Aminopeptidase/LNPEP Antibody [NBP2-81854] - Analysis of Leucyl-cystinyl Aminopeptidase/LNPEP in human lung tissue lysate with Leucyl-cystinyl Aminopeptidase/LNPEP antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.Immunocytochemistry/Immunofluorescence: Leucyl-cystinyl Aminopeptidase/LNPEP Antibody [NBP2-81854] - Immunofluorescence of Leucyl-cystinyl Aminopeptidase/LNPEP in human lung tissue with Leucyl-cystinyl Aminopeptidase/LNPEP antibody at 20 ug/mL.

Rabbit Polyclonal
Species Human
Applications WB, ELISA, ICC/IF

Aquaporin-0 Antibody - BSA Free
NBP2-92773
Western Blot: Aquaporin-0 Antibody [NBP2-92773] - Analysis of extracts of various cell lines, using Aquaporin-0 at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.Immunohistochemistry-Paraffin: Aquaporin-0 Antibody [NBP2-92773] - Rat brain using MIP antibody at dilution of 1:100 (40x lens).

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P


Related Genes

Legionnaires' Disease has been researched against:

Related Pathways

Legionnaires' Disease has been linked to:

Related Diseases

Legionnaires' Disease has been studied in relation to diseases such as:

Related PTMs

Legionnaires' Disease has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Legionnaires' Disease is also known as Disease, Legionnaires', Infection, Legionella Pneumophila, Infections, Legionella Pneumophila, Legionella, Legionella Pneumonia.