Wnt-4 Products

Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT4 is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and DAX1, a gene known to antagonize the testis-determining factor, play a concerted role in both the control of female development and the prevention of testes formation. WNT4 and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue.

Bioinformatics

Entrez	22417 Mouse 54361 Human
Uniprot	BAC23080 Human NM_030761 Human NP_110388 Human NP_110388. Human NP_110388.2 Human P22724 Mouse P56705 Human
Product By Gene ID	54361
Alternate Names	protein Wnt-4 SERKAL wingless-type MMTV integration site family, member 4 WNT-4

Research Areas for Wnt-4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction
Stem Cell Signaling Pathway
Wnt Signaling Pathway