Species: Hu, Rt, Bt, Bv, Ca, Pm, Pm, Rb, Ha, Ma-Op
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB
Host: Rat Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene over expression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
80326 |
Alternate Names |
- FLJ14301
- protein Wnt-10a
- SSPS
- wingless-type MMTV integration site family, member 10A
|
Research Areas for Wnt-10a
Find related products by research area and learn more about each of the different research areas below.
Wnt Signaling Pathway