Species: Hu, Mu, Rt
Applications: WB, IHC, IP, KD
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Sheep Polyclonal
Species: Hu, Mu, Rt, Rb, Po, Bv
Applications: ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: AC
Description
EDD encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.
Bioinformatics
Entrez |
Rat Human Mouse |
Uniprot |
Human Human Human Human |
Product By Gene ID |
51366 |
Alternate Names |
- DD5
- E3 ubiquitin protein ligase, HECT domain containing, 1
- E3 ubiquitin-protein ligase, HECT domain-containing 1
- EC 6.3.2
- EC 6.3.2.-
- EDD1E3 ubiquitin-protein ligase UBR5
- EDDE3 identified by differential display
- hHYD
- HYDFLJ11310
- Hyperplastic discs protein homolog
- KIAA0896MGC57263
- progestin induced protein
- Progestin-induced protein
- ubiquitin protein ligase E3 component n-recognin 5
- ubiquitin-protein ligase
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Research Areas for UBR5/EDD
Find related products by research area and learn more about each of the different research areas below.
DNA Repair