TFF1/pS2 Products

Description

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Bioinformatics

Entrez	21784 Mouse 7031 Human
Uniprot	AAH32811 Human AAH32811.1 Human NM_003225 Human NP_003216 Human P04155 Human Q08423 Mouse
Product By Gene ID	7031
Alternate Names	BCEIbreast cancer, estrogen-inducible sequence expressed in Breast cancer estrogen-inducible protein breast cancer estrogen-inducible sequence D21S21 gastrointestinal trefoil protein pS2 hP1.A HPS2 PNR-2 pNR-2 Polypeptide P1.A Protein pS2 PS2 pS2 trefoil factor 1 trefoil factor, BCE1, human pS2 induced by estrogen from human breast cancercell line M10HP1.A

Research Areas for TFF1/pS2

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer